Evidence map›Paper›PMID 33138832›Full record

ArticleCritical care (London, England)2020

Anxiety, depression and post-traumatic stress disorder management after critical illness: a UK multi-centre prospective cohort study.

Robert Hatch, Duncan Young, Vicki S Barber, John Griffiths, David A Harrison, Peter J Watkinson

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Critical care (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Facing stress and inflammation: From the cell to the planet.World journal of experimental medicine · 2024
    Review
  5. Review
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  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Robert HatchCritical Care Research Group, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. Robert.hatch@doctors.uk.net.ORCID 0000-0002-8176-0831
Duncan YoungCritical Care Research Group, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Vicki S BarberOxford Clinical Trials Research Unit, University of Oxford, Oxford, UK.
John GriffithsAdult Intensive Care Unit, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 9DU, UK.
David A HarrisonIntensive Care National Audit and Research Centre (ICNARC), London, UK.
Peter J WatkinsonCritical Care Research Group, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
University of Oxford · GBIntensive Care National Audit & Research Centre · GBOxford University Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurvivors of critical illness have significant psychopathological comorbidity. The treatments offered by primary health care professionals to affected patients are unstudied.

aimTo report the psychological interventions after GPs received notification of patients who showed severe symptoms of anxiety, depression or Post-Traumatic Stress Disorder.

methodsDesign: Multi-centre prospective cohort sub-study of the ICON study.

settingNHS primary care in the United Kingdom.

participantsAdult patients, November 2006-October 2010 who had received at least 24 h of intensive care, where the general practitioner recorded notification that the patient had reported severe symptoms or caseness using the Hospital Anxiety and Depression Scale (HADS) or the Post-Traumatic Stress Disorder Check List-Civilian (PCL-C).

interventionsWe notified general practitioners (GPs) by post if a patient reported severe symptoms or caseness and sent a postal questionnaire to determine interventions after notification.

main outcome measurePrimary or secondary healthcare interventions instigated by general practitioners following notification of a patient's caseness.

resultsOf the 11,726 patients, sent questionnaire packs containing HADS and PCL-C, 4361 (37%) responded. A notification of severe symptoms was sent to their GP in 25% (1112) of cases. Of notified GPs, 65% (725) responded to our postal questionnaire. Of these 37% (266) had no record of receipt of the original notification. Of the 459 patients where GPs had record of notification (the study group for this analysis), 21% (98) had pre-existing psychopathology. Of those without a pre-existing diagnosis 45% (162) received further psychological assessment or treatment. GP screening or follow-up alone occurred in 18% (64) whilst 27% (98) were referred to mental health services or received drug therapy following notification.

conclusionsPostal questionnaire identifies a burden of psychopathology in survivors of critical illness that have otherwise gone undiagnosed following discharge from an intensive care unit (ICU). After being alerted to the presence of psychological symptoms, GPs instigate treatment in 27% and augmented surveillance in 18% of cases.

trial registrationISRCTN69112866 (assigned 02/05/2006).

Indexed as

AdultAnxietyCohort StudiesCritical IllnessDepressionFemaleHumansMaleMiddle AgedProspective StudiesQuality of LifeStress Disorders, Post-TraumaticSurveys and QuestionnairesUnited KingdomAnxietyCritical illnessDepressionIntensive careMental healthMulti-centreOutcomesPost-traumatic stress disorderPrimary carePsychopathologyQuestionnaire

Identifiers

PMID33138832
PMCPMC7607621
OpenAlexW3096526158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.