SynthesisBMC gastroenterology2020
Adverse events of video capsule endoscopy over the past two decades: a systematic review and proportion meta-analysis.
Synthesis in BMC gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- PillCam COLON 2 for investigation of the colon through direct visualisation: systematic review and economic evaluation.Health technology assessment (Winchester, England) · 2026Pooled it
- Trial
- Trial
- First Brazilian expert consensus for video capsule endoscopy and balloon-assisted enteroscopy.Clinics (Sao Paulo, Brazil) · 2026Article
- A Two-Step Strategy Utilising Fluoroscopy for Resolving Peripheral Airway Impaction by an Aspirated Capsule Endoscope: A Case Report.Respirology case reports · 2026Article
- Edible electronics: Current landscape and emerging pathways.Journal of materials research · 2026Review
- Multicenter study of colon capsule endoscopy in post-polypectomy surveillance.Endoscopy international open · 2026Article
- Expected Values of Artificial Intelligence in Colon Capsule Endoscopy: Artificial Intelligence in Capsule Endoscopy Consortium Position Statement.Endoscopy international open · 2026Article
- Factors predicting conversion from colon capsule endoscopy to conventional optical endoscopy-findings from the CESCAIL study.BMC gastroenterology · 2025Article
- Multicentre Study of 10,369 Symptomatic Patients Comparing the Diagnostic Accuracy of Colon Capsule Endoscopy, Colonoscopy and CT Colonography.Alimentary pharmacology & therapeutics · 2025Article
- Clinical application of capsule endoscopy in children with small bowel disease in Wuhan, China.Frontiers in physiology · 2025Article
- Extended 72-hour patency capsule protocol improves functional patency rates in high-risk patients undergoing capsule endoscopy.World journal of gastrointestinal endoscopy · 2024Article
- Application of small-sized magnetically controlled capsule gastroscopy in upper gastrointestinal diseases screening in asymptomatic individuals.Surgical endoscopy · 2024Article
- Retention of endoscopic capsules in diverticula: Literature review of a capsule endoscopy rarity.Endoscopy international open · 2024Review
- Could Capsule Endoscopy Be Useful in Detection of Suspected Small Bowel Bleeding and IBD-10 Years of Single Center Experience.Diagnostics (Basel, Switzerland) · 2024Article
- A systematic review of capsule aspiration in capsule endoscopy.Annals of translational medicine · 2024Review
- The Role of Capsule Endoscopy in the Diagnosis and Management of Small Bowel Tumors: A Narrative Review.Cancers · 2024Review
- Article
- Bifurcated Lumen Observed on Capsule Endoscopy.The Korean journal of helicobacter and upper gastrointestinal research · 2023Article
- Small Bowel Video Capsule Endoscopy Guidance in Practice: Expert Opinion Report.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
backgroundA full spectrum of video capsule endoscopy (VCE) adverse events over the past two decades has not been evaluated. We aimed to determine pooled rates, predictors and temporal-trend of VCE adverse events over the past two decades.
methodsSystematic search of PubMed and EMBASE for English-language publications reporting VCE adverse events (January 1, 2000 to March 31, 2019). Data were extracted independently by two investigators. Pooled VCE adverse event rates were calculated using the random or fixed model as appropriate. Predictors and temporal-trend of each adverse event were performed by meta-regression analyses.
resultsIn total, 402 studies were identified, including 108,079 VCE procedures. Rate of retention, swallow disorder, aspiration, technical failure, and procedural adverse events were 0.73% (95% confidence interval [CI] 0.59-0.89%), 0.75% (95% CI 0.43-1.13%), 0.00% (95% CI 0.00-0.00%), 0.94% (95% CI 0.65-1.28%), 0.67% (95% CI 0.32-1.10%), respectively; incomplete examination rate of esophagus, stomach, small bowel, and colon were 9.05%, 7.69%, 12.08%, 19.19%, respectively. Patency capsule reduced retention rate by 5.04%, whereas known inflammatory bowel disease increased retention rate by 4.29%. Elder was the risk and protective factor for small bowel incomplete examination (0.30%) and swallow disorder (- 0.72%), respectively. Rates of retention and small bowel incomplete examination significantly declined over time (P = .0006 and P < .0001)..
conclusionsVCE adverse event rates were generally low, and retention and small bowel incomplete examination rates declined over the past two decades. Patients with known inflammatory bowel disease or elder should be alerted to high risk of retention or small bowel incomplete examination (PROSPERO: CRD42019139595).
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