Evidence map›Paper›PMID 33138692›Full record

ArticleVirulence2020

Clinical characteristics of asymptomatic carriers of novel coronavirus disease 2019: A multi-center study in Jiangsu Province.

Jiaxin Chen, Tao Han, Mao Huang, Yi Yang, Futai Shang, Yishan Zheng, Wenjing Zhao, Liang Luo, Xudong Han, Aihua Lin and 9 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Virulence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
0.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Associations between Serum Interleukins (IL-1BioMed research international · 2022
    Pooled it
  4. Pooled it
  5. Article
  6. Lymphocyte Subsets in Mild COVID-19 Pediatric Patients.Turkish archives of pediatrics · 2022
    Article
  7. Review
  8. Characteristics of COVID-19 Patients With SARS-CoV-2 Positivity in Feces.Frontiers in cellular and infection microbiology · 2022
    Article
  9. Article
  10. Liver injury in COVID-19: Known and unknown.World journal of clinical cases · 2021
    Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 12 institutions in 1 country.

Jiaxin ChenDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University , Nanjing, Jiangsu Province, China.
Tao HanDepartment of Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University , Nanjing, Jiangsu Province, China.
Mao HuangDepartment of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University , Nanjing, Jiangsu Province, China.
Yi YangDepartment of Critical Care Medicine, Zhongda Hospital of Southeast University , Nanjing, Jiangsu Province, China.
Futai ShangDepartment of Critical Care Medicine, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University , Huaian, Jiangsu Province, China.
Yishan ZhengDepartment of Critical Care Medicine, Nanjing No.2 Hospital , Nanjing, Jiangsu Province, China.
Wenjing ZhaoDepartment of Critical Care Medicine, The Affiliated Hospital of Xuzhou Medical University , Xuzhou, Jiangsu Province, China.
Liang LuoDepartment of Critical Care Medicine, Wuxi No. 2 People's Hospital , Wuxi, Jiangsu Province, China.
Xudong HanDepartment of Critical Care Medicine, The Third People's Hospital of Nantong City Affiliated to Nantong University , Nantong, Jiangsu Province, China.
Aihua LinDepartment of Critical Care Medicine, Suqian People's Hospital of Nanjing Gulou Hospital Group , Suqian, Jiangsu Province, China.
Hongsheng ZhaoDepartment of Critical Care Medicine, The Affiliated Hospital of Nantong University , Nantong, Jiangsu Province, China.
Qin GuDepartment of Critical Care Medicine, Nanjing Drum Tower Hospital, The Affiliated Nanjing University Medical School , Nanjing, Jiangsu Province, China.
Yi ShiDepartment of Pulmonary and Critical Care Medicine, Nanjing Jinlin Hospital , Nanjing, Jiangsu Province, China.
Jun LiDepartment of Infectious Diseases, The First Affiliated Hospital of Nanjing Medical University , Nanjing, Jiangsu Province, China.
Xingxiang XuDepartment of Pulmonary and Critical Care Medicine, Northern Jiangsu People's Hospital , Yangzhou, Jiangsu Province, China.
Kexi LiuDepartment of Critical Care Medicine, Lianyungang First People's Hospital , Lianyungang, Jiangsu Province, China.
Yijun DengDepartment of Critical Care Medicine, Yancheng First People's Hospital , Yancheng, Jiangsu Province, China.
Enzhi JiaDepartment of Cardiovascular Medicine, The First Affiliated Hospital of Nanjing Medical University , Nanjing, Jiangsu Province, China.
Quan CaoDepartment of Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University , Nanjing, Jiangsu Province, China.
Jiangsu Province Hospital · CNNanjing Medical University · CNAffiliated Hospital of Nantong University · CNHuaian First People’s Hospital · CNNanjing Drum Tower Hospital · CNNantong University · CNNorthern Jiangsu People's Hospital · CNThe First People’s Hospital of Lianyungang · CNWuxi No.2 People's Hospital · CNXuzhou Medical College · CNYancheng First People's Hospital · CNZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asymptomatic SARS-CoV-2-infected individuals are thought to play major roles in virus transmission. This study aimed to analyze the characteristics of asymptomatic carriers with COVID-19 to control the spread of the virus. We retrospectively investigated the clinical characteristics of 648 consecutive subjects who were enrolled in the study and were divided into asymptomatic carriers, mild cases, ordinary cases, severe or critical cases, and evaluated their impact on disease severity by means of Spearman correlation and multiple regression analyses. Receiver operating characteristic curve analysis was conducted to determine the optimum cutoff levels of laboratory findings for diagnostic predictors of asymptomatic carriers of COVID-19. In our study, a total of 648 subjects on admission with a mean age of 45.61 y including 345 males and 303 females were enrolled in our study. The leukocyte, lymphocyte, eosinophil, platelet, C-reactive protein, interleukin-6, CD3+, CD4+, and CD8 + T lymphocyte levels, and the erythrocyte sedimentation rate differed significantly among the groups (all

Indexed as

AdolescentAdultAgedAged, 80 and overAsymptomatic InfectionsChildChild, PreschoolChinaCoronavirus InfectionsCOVID-19CytokinesDisease ProgressionFemaleHumansInfantInflammationCytokinesasymptomatic carriersCOVID-19disease severity of COVID-19immune responseinflammatory markerNovel coronavirus disease-19SARS-CoV-2severe acute respiratory syndrome coronavirus 2

Identifiers

PMID33138692
PMCPMC7644248
OpenAlexW3094921038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.