Evidence map›Paper›PMID 33138297›Full record

ArticleMolecules (Basel, Switzerland)2020

Salinosporamide A, a Marine-Derived Proteasome Inhibitor, Inhibits T Cell Activation through Regulating Proliferation and the Cell Cycle.

Hyun-Su Lee, Gil-Saeng Jeong

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hyun-Su LeeCollege of Pharmacy, Keimyung University, 1095 Dalgubeol-daero, Daegu 42601, Korea.
Gil-Saeng JeongCollege of Pharmacy, Keimyung University, 1095 Dalgubeol-daero, Daegu 42601, Korea.
Keimyung University · KR

Funding

Basic Science Research Program through the National Research Foundation of Korea (NRF) NRF-2016R1A6A1A03011325
6 · The paper itself

Abstract

The appropriate regulation of T cell activity under inflammatory conditions is crucial for maintaining immune homeostasis. Salinosporamide A discovered as a self-resistance product from the marine bacterium

Indexed as

LactonesProteasome InhibitorsPyrrolesAnimalsAquatic OrganismsCD4-Positive T-LymphocytesCell ProliferationHumansJurkat CellsLymphocyte ActivationMAP Kinase Signaling SystemMiceMicromonosporaceaeLactonesmarizomibProteasome InhibitorsPyrrolescell cyclemarine life-derivedproteasome inhibitorsalinosporamide AT cell proliferation

Identifiers

PMID33138297
PMCPMC7663257
OpenAlexW3097449338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.