Evidence map›Paper›PMID 33138200›Full record

ArticleMolecules (Basel, Switzerland)2020

The Influence of pH Values on the Rheological, Textural and Release Properties of Carbomer Polacril

Yuliia Maslii, Olena Ruban, Giedre Kasparaviciene, Zenona Kalveniene, Anna Materiienko, Liudas Ivanauskas, Agne Mazurkeviciute, Dalia M Kopustinskiene, Jurga Bernatoniene

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 54 citations in OpenAlex.

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  15. Development and Evaluation ofTurkish journal of pharmaceutical sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Yuliia MasliiDepartment of Industrial Technology of Drugs, National University of Pharmacy, 61002 Kharkiv, Ukraine.ORCID 0000-0002-8968-0262
Olena RubanDepartment of Industrial Technology of Drugs, National University of Pharmacy, 61002 Kharkiv, Ukraine.
Giedre KasparavicieneDepartment of Drug Technology and Social Pharmacy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.ORCID 0000-0002-4293-7454
Zenona KalvenieneDepartment of Drug Technology and Social Pharmacy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.
Anna MateriienkoDepartment of Quality, Standardization and Certification of Drugs, National University of Pharmacy, 61002 Kharkiv, Ukraine.ORCID 0000-0003-4184-2944
Liudas IvanauskasDepartment of Analytical Chemistry, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.
Agne MazurkeviciuteDepartment of Clinical Pharmacy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.
Dalia M KopustinskieneInstitute of Pharmaceutical Technologies, Medical Academy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.ORCID 0000-0002-3399-2849
Jurga BernatonieneDepartment of Drug Technology and Social Pharmacy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.ORCID 0000-0003-1744-2932
Lithuanian University of Health Sciences · LTNational University of Pharmacy · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The physicochemical properties, especially pH value of dental medicines, have significant influence on the health of oral cavity tissues. The pH of formulations should correspond to the value of saliva pH (5.5-8.0). For carbomer-based gels, the required pH value is obtained by neutralizing them with alkaline components, which leads to their structuring (thickening). This affects the physical properties of the gel, its residence time at the application site and the rate of release of active pharmaceutical ingredient. Therefore, the main purpose of this study is to evaluate the rheological, textural, and biopharmaceutical properties of Carbomer Polacril

Indexed as

Acrylic ResinsDentifricesGelsHydrogen-Ion ConcentrationPlant ExtractsRheologyViscosityAcrylic ResinscarbomerDentifricesGelsPlant ExtractsCarbomer Polacril® 40P-based geloral mucosa diseasesperiodontal tissuepHrelease testrheological studiestextural analysis

Identifiers

PMID33138200
PMCPMC7663699
OpenAlexW3096720409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.