ArticleInternational journal of molecular sciences2020
Mechanical and Biocompatibility Properties of Calcium Phosphate Bioceramics Derived from Salmon Fish Bone Wastes.
Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 53 citations in OpenAlex.
- Mechanical Enhancement and Fracture Mechanisms of SLA Photopolymer Composites Reinforced with Fish Bone Ash.Polymers · 2026Article
- Criteria for the Characterization of Seafood Byproducts to Allow Tracing Their Geographic Origin.Foods (Basel, Switzerland) · 2026Review
- Gut Microbiota in the Hepato-Cardiorenal Axis: Microbial Metabolites, Inflammation, and Emerging Therapeutic Targets.Current pharmaceutical design · 2026Review
- Sustainable Valorization of Mussel Shell Waste: Processing for Calcium Carbonate Recovery and Hydroxyapatite Production.Journal of functional biomaterials · 2025Article
- Innovative applications of 3D printing in personalized medicine and complex drug delivery systems.iScience · 2025Review
- Effect of vacancies on blue-colored calcium phosphate scaffolds derived from Nile tilapia bone powder.Scientific reports · 2025Article
- Elemental composition, physicochemical properties, and calcium bioavailability of calcined gill powders from Asian seabass and catfish.Food chemistry: X · 2025Article
- 3D-Printed Cell-Instructive Scaffolds Based onACS biomaterials science & engineering · 2025Article
- Extraction and Characterization of Biogenic Nano-Calcium Derived fromFood technology and biotechnology · 2025Article
- Efficient Hydroxyapatite Extraction from Salmon Bone Waste: An Improved Lab-Scaled Physico-Chemico-Biological Process.Molecules (Basel, Switzerland) · 2024Article
- Hybrid Polymer-Inorganic Materials with Hyaluronic Acid as Controlled Antibiotic Release Systems.Materials (Basel, Switzerland) · 2023Article
- Trash to Treasure: An Up-to-Date Understanding of the Valorization of Seafood By-Products, Targeting the Major Bioactive Compounds.Marine drugs · 2023Review
- Tissue-Engineered Nanomaterials Play Diverse Roles in Bone Injury Repair.Nanomaterials (Basel, Switzerland) · 2023Review
- Preparation, Characterization, and Biological Properties of Hydroxyapatite from Bigeye Snapper (International journal of molecular sciences · 2023Article
- Potential Cosmetic Active Ingredients Derived from Marine By-Products.Marine drugs · 2022Review
- The Relationship between Osteoinduction and Vascularization: Comparing the Ectopic Bone Formation of Five Different Calcium Phosphate Biomaterials.Materials (Basel, Switzerland) · 2022Article
- Novel Trends into the Development of Natural Hydroxyapatite-Based Polymeric Composites for Bone Tissue Engineering.Polymers · 2022Review
- A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards.Nanomaterials (Basel, Switzerland) · 2021Review
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Authors and funding
11 authors at 8 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural calcium phosphates derived from fish wastes are a promising material for biomedical application. However, their sintered ceramics are not fully characterized in terms of mechanical and biological properties. In this study, natural calcium phosphate was synthesized through a thermal calcination process from salmon fish bone wastes. The salmon-derived calcium phosphates (sCaP) were sintered at different temperatures to obtain natural calcium phosphate bioceramics and then were investigated in terms of their microstructure, mechanical properties and biocompatibility. In particular, this work is concerned with the effects of grain size on the relative density and microhardness of the sCaP bioceramics. Ca/P ratio of the sintered sCaP ranged from 1.73 to 1.52 when the sintering temperature was raised from 1000 to 1300 °C. The crystal phase of all the sCaP bioceramics obtained was biphasic and composed of hydroxyapatite (HA) and tricalcium phosphate (TCP). The density and microhardness of the sCaP bioceramics increased in the temperature interval 1000-1100 °C, while at temperatures higher than 1100 °C, these properties were not significantly altered. The highest compressive strength of 116 MPa was recorded for the samples sintered at 1100 °C. In vitro biocompatibility was also examined in the behavior of osteosarcoma (Saos-2) cells, indicating that the sCaP bioceramics had no cytotoxicity effect. Salmon-derived biphasic calcium phosphates (BCP) have the potential to contribute to the development of bone substituted materials.
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