Evidence map›Paper›PMID 33138158›Full record

ArticleJournal of clinical medicine2020

Predictive Value of Bleb Vascularity after Mitomycin C Augmented Trabeculectomy.

Aleksandra Wlaź, Anna Kuna, Agnieszka Wilkos-Kuc, Agnieszka Rozegnał-Madej, Tin Aung, Tomasz Żarnowski

Abstract read
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Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aleksandra WlaźDepartment of Diagnostics and Microsurgery of Glaucoma, Medical University, Chmielna 1, 20-079 Lublin, Poland.ORCID 0000-0001-8107-7883
Anna KunaDepartment of Diagnostics and Microsurgery of Glaucoma, Medical University, Chmielna 1, 20-079 Lublin, Poland.
Agnieszka Wilkos-KucDepartment of Diagnostics and Microsurgery of Glaucoma, Medical University, Chmielna 1, 20-079 Lublin, Poland.
Agnieszka Rozegnał-MadejDepartment of Diagnostics and Microsurgery of Glaucoma, Medical University, Chmielna 1, 20-079 Lublin, Poland.
Tin AungSingapore Eye Research Institute & Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751, Singapore.
Tomasz ŻarnowskiDepartment of Diagnostics and Microsurgery of Glaucoma, Medical University, Chmielna 1, 20-079 Lublin, Poland.ORCID 0000-0002-6978-7417

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the relationship between bleb vascularity and surgical outcome one year after mitomycin C (MMC) augmented trabeculectomy.

methodsThis was a prospective study of 51 eyes of 44 patients after MMC-augmented primary trabeculectomy with follow-up of 12 months. The total vessel area of a bleb was measured with ImageJ software on color photographs of the bleb on day 1 and 14, then months 1, 3, 6 and 12 after trabeculectomy. Blebs were classified clinically as successful (intraocular pressure (IOP) ≤ 18 mmHg and a >30% reduction in IOP without antiglaucoma medications or additional surgical interventions) or failed. Linear regression analysis was performed to determine the correlation of bleb vascularity with IOP and outcome.

resultsAt 1 year, 40 eyes (78.4%) were classified as successful and 11 eyes (21.6%) as failed. The mean bleb vascularity at 1, 3 and 12 months after surgery was significantly higher in failed blebs (16.31% vs. 13.01%,

conclusionsIn this prospective study, we demonstrated a strong relationship between bleb vascularity and the surgical outcomes of trabeculectomy. Vascularity of the filtering bleb during early postoperative period was not correlated with IOP or success of trabeculectomy at one year. Increased bleb vascularity 1, 3 and 12 months after trabeculectomy appears to predict surgical failure at 1 year after trabeculectomy.

Indexed as

filtering blebglaucoma surgerytrabeculectomyvessel areawound healing

Identifiers

PMID33138158
PMCPMC7692207

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.