Evidence map›Paper›PMID 33138125›Full record

ArticlePolymers2020

Photocurable Methacrylate Derivatives of Polylactide: A Two-Stage Synthesis in Supercritical Carbon Dioxide and 3D Laser Structuring.

Vladislav S Kaplin, Nikolay N Glagolev, Valentina T Shashkova, Irina A Matveeva, Ilya V Shershnev, Tatyana S Zarkhina, Nikita V Minaev, Nadezhda A Aksenova, Boris S Shavkuta, Evgeny A Bezrukov and 5 more

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Vladislav S KaplinSemenov Federal Research Center of Chemical Physics, 4 Kosygin St., 119991 Moscow, Russia.ORCID 0000-0003-4751-6437
Nikolay N GlagolevSemenov Federal Research Center of Chemical Physics, 4 Kosygin St., 119991 Moscow, Russia.
Valentina T ShashkovaSemenov Federal Research Center of Chemical Physics, 4 Kosygin St., 119991 Moscow, Russia.
Irina A MatveevaSemenov Federal Research Center of Chemical Physics, 4 Kosygin St., 119991 Moscow, Russia.
Ilya V ShershnevSemenov Federal Research Center of Chemical Physics, 4 Kosygin St., 119991 Moscow, Russia.
Tatyana S ZarkhinaSemenov Federal Research Center of Chemical Physics, 4 Kosygin St., 119991 Moscow, Russia.
Nikita V MinaevResearch center "Crystallography and Photonics", Institute of Photonic Technologies, 2 Pionerskaya St., Troitsk, 108840 Moscow, Russia.ORCID 0000-0002-9931-0118
Nadezhda A AksenovaSemenov Federal Research Center of Chemical Physics, 4 Kosygin St., 119991 Moscow, Russia.
Boris S ShavkutaResearch center "Crystallography and Photonics", Institute of Photonic Technologies, 2 Pionerskaya St., Troitsk, 108840 Moscow, Russia.
Evgeny A BezrukovInstitute for Urology and Reproductive Health, Sechenov University, 8 Trubetskaya St., 119991 Moscow, Russia.
Aleksandr S KopylovSemenov Federal Research Center of Chemical Physics, 4 Kosygin St., 119991 Moscow, Russia.
Daria S KuznetsovaInstitute of Experimental Oncology and Biomedical Technologies, Privolzhsky Research Medical University, Minin and Pozharsky Sq. 10/1, 603950 Nizhny Novgorod, Russia.
Anastasiia I ShpichkaInstitute for Regenerative Medicine, Sechenov University, 8 Trubetskaya St., 119991 Moscow, Russia.ORCID 0000-0002-9918-9979
Peter S TimashevSemenov Federal Research Center of Chemical Physics, 4 Kosygin St., 119991 Moscow, Russia.
Anna B SolovievaSemenov Federal Research Center of Chemical Physics, 4 Kosygin St., 119991 Moscow, Russia.
Semenov Institute of Chemical Physics · RUSechenov University · RUFederal Scientific Research Centre Crystallography and Photonics · RUMoscow State University of Fine Chemical Technologies · RUPrivolzhsky Research Medical University · RU

Funding

Russian Foundation for Basic Research 18-29-06019 mkRussian Foundation for Basic Research 18-29-06059 mkRussian Government assignment V. 46.14, № 0082-2014-0006Russian Science Support Foundation 19-75-10008
6 · The paper itself

Abstract

A two-stage polylactide modification was performed in the supercritical carbon dioxide medium using the urethane formation reaction. The modification resulted in the synthesis of polymerizable methacrylate derivatives of polylactide for application in the spatial 3D structuring by laser stereolithography. The use of the supercritical carbon dioxide medium allowed us to obtain for the first time polymerizable oligomer-polymer systems in the form of dry powders convenient for further application in the preparation of polymer compositions for photocuring. The photocuring of the modified polymers was performed by laser stereolithography and two-photon crosslinking. Using nanoindentation, we found that Young's modulus of the cured compositions corresponded to the standard characteristics of implants applied in regenerative medicine. As shown by thermogravimetric analysis, the degree of crosslinking and, hence, the local stiffness of scaffolds were determined by the amount of the crosslinking agent and the photocuring regime. No cytotoxicity was observed for the structures.

Indexed as

photopolymerizationpolylactidesupercritical carbon dioxidetissue engineeringtwo-photon polymerization

Identifiers

PMID33138125
PMCPMC7692848
OpenAlexW3095196577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.