Evidence map›Paper›PMID 33138052›Full record

ArticleCancers2020

Plasma Predictive Features in Treating EGFR-Mutated Non-Small Cell Lung Cancer.

Christi M J Steendam, G D Marijn Veerman, Melinda A Pruis, Peggy Atmodimedjo, Marthe S Paats, Cor van der Leest, Jan H von der Thüsen, David C Y Yick, Esther Oomen-de Hoop, Stijn L W Koolen and 6 more

Registry-linked trialAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05221372 (proSpecTive sAmpling in dRiver muTation Pulmonary Oncology Patients on Tyrosine Kinase Inhibitors), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05221372 recruitingnot on this map

proSpecTive sAmpling in dRiver muTation Pulmonary Oncology Patients on Tyrosine Kinase Inhibitors

Typeobservational_patient_registrySponsorErasmus Medical CenterRan2017 to 2031Enrolled1,300ConditionsNon Small Cell Lung Cancer, Liquid Biopsy, Tyrosine Kinase Inhibitor
3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Connecting the dots: (RANKLTranslational lung cancer research · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Christi M J SteendamDepartment of Pulmonology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
G D Marijn VeermanDepartment of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Melinda A PruisDepartment of Pulmonology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Peggy AtmodimedjoDepartment of Pathology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Marthe S PaatsDepartment of Pulmonology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Cor van der LeestDepartment of Pulmonology, Amphia Hospital, 4818 CK Breda, The Netherlands.
Jan H von der ThüsenDepartment of Pathology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-9699-4860
David C Y YickDepartment of Pathology, Amphia Hospital, 4818 CK Breda, The Netherlands.
Esther Oomen-de HoopDepartment of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-2506-3852
Stijn L W KoolenDepartment of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Winand N M DinjensDepartment of Pathology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Ron H N van SchaikDepartment of Clinical Chemistry, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Ron H J MathijssenDepartment of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Joachim G J V AertsDepartment of Pulmonology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Hendrikus Jan DubbinkDepartment of Pathology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.
Anne-Marie C DingemansDepartment of Pulmonology, Erasmus MC Cancer Institute, University Medical Center, 3015 GD Rotterdam, The Netherlands.

Funding

AstraZeneca 2604226313AstraZeneca 2604937054
6 · The paper itself

Abstract

Although epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are the preferred treatment for patients with

Indexed as

cfDNAEGFRNSCLCpharmacokineticsplasma conversionT790M mutationTKITP53 mutation

Identifiers

PMID33138052
PMCPMC7692448

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.