Evidence map›Paper›PMID 33137990›Full record

ArticleInternational journal of molecular sciences2020

Blood Profile of Cytokines, Chemokines, Growth Factors, and Redox Biomarkers in Response to Different Protocols of Treadmill Running in Rats.

Elżbieta Supruniuk, Mateusz Maciejczyk, Anna Zalewska, Jan Górski, Adrian Chabowski

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elżbieta SupruniukDepartment of Physiology, Medical University of Bialystok, 2C Mickiewicza Street, 15-222 Bialystok, Poland.ORCID 0000-0002-3595-4707
Mateusz MaciejczykDepartment of Hygiene, Epidemiology and Ergonomics, Medical University of Bialystok, 2C Mickiewicza Street, 15-233 Bialystok, Poland.ORCID 0000-0001-5609-3187
Anna ZalewskaExperimental Dentistry Laboratory, Medical University of Bialystok, 24a M. Sklodowskiej-Curie Street, 15-274 Bialystok, Poland.ORCID 0000-0003-4562-0951
Jan GórskiDepartment of Medical Sciences, Lomza State University of Applied Sciences, 18-400 Lomza, Poland.
Adrian ChabowskiDepartment of Physiology, Medical University of Bialystok, 2C Mickiewicza Street, 15-222 Bialystok, Poland.ORCID 0000-0002-7407-8156
Medical University of Białystok · PLAkademia Łomżyńska · PL

Funding

Uniwersytet Medyczny w Bialymstoku SUB/1/DN/19/005/1118Uniwersytet Medyczny w Białymstoku SUB/1/DN/20/011/1118
6 · The paper itself

Abstract

Both positive and negative aspects of sport performance are currently considered. The aim of our study was to determine time- and intensity-dependent effects of a single exercise bout on redox and inflammatory status. The experiment was performed on 40 male Wistar rats subjected to treadmill running for 30 min with the speed of 18 m/min (M30) or 28 m/min (F30), or for 2 h with the speed of 18 m/min (M120). Immunoenzymatic and spectrophotometric methods were applied to assess the levels of pro-inflammatory and anti-inflammatory cytokines, chemokines, growth factors, the antioxidant barrier, redox status, oxidative damage products, nitrosative stress, and their relationships with plasma non-esterified fatty acids. Treadmill running caused a reduction in the content of monocyte chemoattractant protein-1 (MCP1) and nitric oxide (M30, M120, F30 groups) as well as macrophage inflammatory protein-1α (MIP-1α) and regulated on activation, normal T-cell expressed and secreted (RANTES) (M30, F30 groups). We also demonstrated an increase in catalase activity as well as higher levels of reduced glutathione, advanced oxidation protein products, lipid hydroperoxides, malondialdehyde (M30, M120, F30 groups), and advanced glycation end products (F30 group). The presented findings showed the activation of antioxidative defense in response to increased reactive oxygen species' production after a single bout of exercise, but it did not prevent oxidative damage of macromolecules.

Indexed as

Physical Conditioning, AnimalAnimalsAntioxidantsBiomarkersChemokinesCytokinesExercise TestIntercellular Signaling Peptides and ProteinsMaleOxidation-ReductionOxidative StressRatsRats, WistarAntioxidantsBiomarkersChemokinesCytokinesIntercellular Signaling Peptides and Proteinschemokinescytokinesexerciseinflammationoxidative stress

Identifiers

PMID33137990
PMCPMC7663152
OpenAlexW3096238836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.