Evidence map›Paper›PMID 33137930›Full record

ArticleMolecules (Basel, Switzerland)2020

In Vitro and In Vivo Biological Activity of Berberine Chloride against Uropathogenic

Giulio Petronio Petronio, Marco Alfio Cutuli, Irene Magnifico, Noemi Venditti, Laura Pietrangelo, Franca Vergalito, Antonella Pane, Giovanni Scapagnini, Roberto Di Marco

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Berberine Extends Lifespan inAntioxidants (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Nutraceuticals in Pregnancy: A Special Focus on Probiotics.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Emerging Evidence onMicroorganisms · 2022
    Review
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Giulio Petronio PetronioDepartment of Health and Medical Sciences "V. Tiberio", University of Molise Via de Sanctis 3, III Ed. Polifunzionale, 86100 Campobasso (CB) Molise, Italy.ORCID 0000-0002-5098-7785
Marco Alfio CutuliDepartment of Health and Medical Sciences "V. Tiberio", University of Molise Via de Sanctis 3, III Ed. Polifunzionale, 86100 Campobasso (CB) Molise, Italy.
Irene MagnificoDepartment of Health and Medical Sciences "V. Tiberio", University of Molise Via de Sanctis 3, III Ed. Polifunzionale, 86100 Campobasso (CB) Molise, Italy.
Noemi VendittiDepartment of Health and Medical Sciences "V. Tiberio", University of Molise Via de Sanctis 3, III Ed. Polifunzionale, 86100 Campobasso (CB) Molise, Italy.
Laura PietrangeloDepartment of Health and Medical Sciences "V. Tiberio", University of Molise Via de Sanctis 3, III Ed. Polifunzionale, 86100 Campobasso (CB) Molise, Italy.
Franca VergalitoDepartment of Agricultural, Environmental and Food Sciences (DiAAA), University of Molise, Via De Sanctis 3, III Ed. Polifunzionale, 86100 Campobasso, Italy.
Antonella PaneDepartment of Agricultural, Food and Environment, University of Catania, Via S. Sofia, 100, 95123 Catania, Italy.ORCID 0000-0002-8457-1788
Giovanni ScapagniniDepartment of Health and Medical Sciences "V. Tiberio", University of Molise Via de Sanctis 3, III Ed. Polifunzionale, 86100 Campobasso (CB) Molise, Italy.ORCID 0000-0003-1592-5586
Roberto Di MarcoDepartment of Health and Medical Sciences "V. Tiberio", University of Molise Via de Sanctis 3, III Ed. Polifunzionale, 86100 Campobasso (CB) Molise, Italy.ORCID 0000-0001-5075-4597
University of Molise · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Berberine is an alkaloid of the protoberberine type used in traditional oriental medicine. Its biological activities include documented antibacterial properties against a wide variety of microorganisms; nonetheless, its use against

Indexed as

Escherichia coli InfectionsAnimalsAnti-Bacterial AgentsBerberineDisease Models, AnimalHemolymphLarvaMothsUropathogenic Escherichia coliAnti-Bacterial AgentsBerberineantimicrobial activityberberine chlorideGalleria mellonellahost–pathogen interactionsUPEC

Identifiers

PMID33137930
PMCPMC7662377
OpenAlexW3097765871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.