ArticleMolecules (Basel, Switzerland)2020
Tert-butyl-(4-hydroxy-3-((3-(2-methylpiperidin-yl)propyl)carbamoyl)phenyl)carbamate Has Moderated Protective Activity in Astrocytes Stimulated with Amyloid Beta 1-42 and in a Scopolamine Model.
Raúl Horacio Camarillo-López, Maricarmen Hernández Rodríguez, Mónica Adriana Torres-Ramos, Ivonne Maciel Arciniega-Martínez, Iohanan Daniel García-Marín, José Correa Basurto, Juan Vicente Méndez Méndez, Martha Cecilia Rosales-Hernández
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Raúl Horacio Camarillo-LópezLaboratorio de Biofísica y biocatálisis, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Diaz Mirón s/n, 11340 Ciudad de México, Mexico.
Maricarmen Hernández RodríguezLaboratorio de Biofísica y biocatálisis, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Diaz Mirón s/n, 11340 Ciudad de México, Mexico.
Mónica Adriana Torres-RamosUnidad Periférica de Neurociencias, Facultad de Medicina UNAM-Instituto Nacional de Neurología y Neurocirugía, MVS-SSA, Insurgentes sur 3877, La Fama, Tlalpan, 14269 Ciudad de México, Mexico.ORCID 0000-0002-8900-4037 Ivonne Maciel Arciniega-MartínezLaboratorio de Inmunidad de Mucosas, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón s/n, 11340 Ciudad de México, Mexico.
Iohanan Daniel García-MarínLaboratorio de Biofísica y biocatálisis, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Diaz Mirón s/n, 11340 Ciudad de México, Mexico.
José Correa BasurtoLaboratorio de Diseño y Desarrollo de Nuevos Fármacos e Innovación Biotecnológica, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, 11340 Ciudad de México, Mexico.
Juan Vicente Méndez MéndezCentro de Nanociencias y Micro y Nanotecnologías, Instituto Politécnico Nacional. Av. Luis Enrique Erro s/n, Nueva Industrial Vallejo, Gustavo A. Madero, 07738 Ciudad de México, Mexico.
Martha Cecilia Rosales-HernándezLaboratorio de Biofísica y biocatálisis, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Diaz Mirón s/n, 11340 Ciudad de México, Mexico.ORCID 0000-0003-0012-580X Funding
Consejo Nacional de Ciencia y Tecnología CB286653, 37634, 254600 and 782SIPCOFAA-IPN, SIP20195089
6 · The paper itselfAbstract
Alzheimer's disease (AD) is a neurodegenerative disease with no cure nowadays; there is no treatment either to prevent or to stop its progression. In vitro studies suggested that tert-butyl-(4-hydroxy-3-((3-(2-methylpiperidin-yl)propyl)carbamoyl)phenyl) carbamate named the
Indexed as
Alzheimer DiseaseCarbamatesNeuroprotective AgentsAmyloid beta-PeptidesAnimalsAstrocytesDisease Models, AnimalHumansPeptide FragmentsRatsScopolamineAmyloid beta-Peptidesamyloid beta-protein (1-42)CarbamatesNeuroprotective AgentsPeptide FragmentsScopolamineAlzheimer’s diseaseamyloid beta peptide (Aβ1-42)astrocyte cellsM4 compoundscopolamineβ-secretase
Identifiers
PMID33137907
PMCPMC7672627
What OpenQuestion holds
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