Evidence map›Paper›PMID 33137846›Full record

ReviewWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology2021

Two-dimensional metal organic frameworks for biomedical applications.

Shreedevi Arun Kumar, Bhuvaneshwari Balasubramaniam, Sukanya Bhunia, Manish K Jaiswal, Kartikey Verma, Prateek, Ali Khademhosseini, Raju Kumar Gupta, Akhilesh K Gaharwar

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Periodic Table of Immunomodulatory Elements and Derived Two-Dimensional Biomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. 2D layered nanomaterials for therapeutics delivery.Current opinion in biomedical engineering · 2021
    Article
  14. Metal-Organic Frameworks (MOFs) for Cancer Therapy.Materials (Basel, Switzerland) · 2021
    Article
  15. Emerging 2D Nanomaterials for Biomedical Applications.Materials today (Kidlington, England) · 2021
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shreedevi Arun KumarDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, Texas, USA.
Bhuvaneshwari BalasubramaniamDepartment of Chemical Engineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India.ORCID 0000-0001-6883-5731
Sukanya BhuniaDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, Texas, USA.
Manish K JaiswalDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, Texas, USA.
Kartikey VermaDepartment of Chemical Engineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India.
PrateekDepartment of Chemical Engineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India.ORCID 0000-0002-7305-5550
Ali KhademhosseiniTerasaki Institute for Biomedical Innovation, Los Angeles, California, USA.ORCID 0000-0002-2692-1524
Raju Kumar GuptaDepartment of Chemical Engineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India.ORCID 0000-0002-5537-8057
Akhilesh K GaharwarDepartment of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, Texas, USA.ORCID 0000-0002-0284-0201

Funding

Mineralomics: Designing mineral based therapeutics to control and direct cell functionDP2EB026265 · NIBIB · TEXAS ENGINEERING EXPERIMENT STATION · PI GAHARWAR, AKHILESH K. · 2017 to 2021
$2.4M
NIBIB NIH HHS DP2 EB026265
6 · The paper itself

Abstract

Two-dimensional (2D) metal organic frameworks (MOFs), are an emerging class of layered nanomaterials with well-defined structure and modular composition. The unique pore structure, high flexibility, tunability, and ability to introduce desired functionality within the structural framework, have led to potential use of MOFs in biomedical applications. This article critically reviews the application of 2D MOFs for therapeutic delivery, tissue engineering, bioimaging, and biosensing. Further, discussion on the challenges and strategies in next generation of 2D MOFs are also included. This article is categorized under: Nanotechnology Approaches to Biology > Nanoscale Systems in Biology.

Indexed as

Metal-Organic FrameworksNanostructuresBiosensing TechniquesDiagnostic ImagingDrug Delivery SystemsTissue EngineeringMetal-Organic Frameworksbioimagingbiosensingdrug deliverymetal organic frameworks (MOFs)tissue engineering

Identifiers

PMID33137846
PMCPMC13050496

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.