ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2020
Neuromuscular involvement in COVID-19 critically ill patients.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05572853 (Analysis of Electrical Activity of Respiratory Muscles in Patients Undergoing Oxygen Therapy With COVID-19), which is not on this map. Cited by 63 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Analysis of Electrical Activity of Respiratory Muscles in Patients Undergoing Oxygen Therapy With COVID-19: Cross-sectional Study
Who cites it
63 citing papers in PubMed, 3 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Electrophysiological assessment in patients with COVID-19-related peripheral neuropathies and myopathies: a systematic review.Journal of neurophysiology · 2023Pooled it
- The role of COVID-19 in myopathy: incidence, causes, treatment, and prevention.Journal of medicine and life · 2022Pooled it
- COVID-19 associated cranial nerve neuropathy: A systematic review.Bosnian journal of basic medical sciences · 2022Pooled it
- Effect of intensive care unit hospitalization for acute respiratory distress syndrome on strength, fatigue and motor unit behaviour.Scientific reports · 2026Article
- Article
- Review
- Incidence and risk factors of peripheral nerve injuries 3 months after ICU discharge: a retrospective study comparing COVID-19 and non-COVID-19 critically ill survivors.Journal of anesthesia, analgesia and critical care · 2024Article
- Diagnosis of "intensive care unit-acquired weakness" and "critical illness myopathy": Do the diagnostic criteria need to be revised?Clinical neurophysiology practice · 2024Article
- Muscle strength/intensive care unit acquired weakness in COVID-19 and non-COVID-19 patients.Nursing in critical care · 2023Article
- Postacute Sequelae of SARS-CoV-2: Musculoskeletal Conditions and Pain.Physical medicine and rehabilitation clinics of North America · 2023Review
- [The problem of long/post-COVID in expert assessments].Unfallchirurgie (Heidelberg, Germany) · 2023Review
- Sex-differences in the longitudinal recovery of neuromuscular function in COVID-19 associated acute respiratory distress syndrome survivors.Frontiers in medicine · 2023Article
- Prediction of muscular paralysis disease based on hybrid feature extraction with machine learning technique for COVID-19 and post-COVID-19 patients.Personal and ubiquitous computing · 2023Article
- Acute Phrenic Neuropathy and Diaphragmatic Dysfunction as a Complication of COVID-19: A Report of Four Cases.Cureus · 2023Article
- Corneal confocal microscopy identifies corneal nerve fibre loss and increased dendritic cells in patients with long COVID.The British journal of ophthalmology · 2022Article
- Review
- Body Weight May Have a Role on Neuropathy and Mobility after Moderate to Severe COVID-19: An Exploratory Study.Medicina (Kaunas, Lithuania) · 2022Article
- Article
- The Effects of COVID-19 on Skeletal Muscles, Muscle Fatigue and Rehabilitation Programs Outcomes.Medicina (Kaunas, Lithuania) · 2022Review
- Review
3 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCoronavirus disease 2019 (COVID-19) has a high incidence of intensive care admittance due to the severe acute respiratory syndrome (SARS). Intensive care unit (ICU)-acquired weakness (ICUAW) is a common complication of ICU patients consisting of symmetric and generalised weakness. The aim of this study was to determine the presence of myopathy, neuropathy or both in ICU patients affected by COVID-19 and whether ICUAW associated with COVID-19 differs from other aetiologies.
methodsTwelve SARS CoV-2 positive patients referred with the suspicion of critical illness myopathy (CIM) or polyneuropathy (CIP) were included between March and May 2020. Nerve conduction and concentric needle electromyography were performed in all patients while admitted to the hospital. Muscle biopsies were obtained in three patients.
resultsFour patients presented signs of a sensory-motor axonal polyneuropathy and seven patients showed signs of myopathy. One muscle biopsy showed scattered necrotic and regenerative fibres without inflammatory signs. The other two biopsies showed non-specific myopathic findings.
conclusionsWe have not found any distinctive features in the studies of the ICU patients affected by SARS-CoV-2 infection. SIGNIFICANCE: Further studies are needed to determine whether COVID-19-related CIM/CIP has different features from other aetiologies. Neurophysiological studies are essential in the diagnosis of these patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.