Evidence map›Paper›PMID 33137159›Full record

SynthesisPloS one2020

Perioperative and anesthesia-related cardiac arrest and mortality rates in Brazil: A systematic review and proportion meta-analysis.

Leandro G Braz, José R C Braz, Marilia P Modolo, Jose E Corrente, Rafael Sanchez, Mariana Pacchioni, Julia B Cury, Iva B Soares, Mariana G Braz

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Leandro G BrazDepartment of Anesthesiology, Botucatu Medical School, Sao Paulo State University-UNESP, São Paulo, Brazil.ORCID 0000-0002-1927-8729
José R C BrazDepartment of Anesthesiology, Botucatu Medical School, Sao Paulo State University-UNESP, São Paulo, Brazil.
Marilia P ModoloDepartment of Anesthesiology, Botucatu Medical School, Sao Paulo State University-UNESP, São Paulo, Brazil.
Jose E CorrenteDepartment of Biostatistics, Institute of Biosciences, Sao Paulo State University-UNESP, São Paulo, Brazil.
Rafael SanchezDepartment of Anesthesiology, Botucatu Medical School, Sao Paulo State University-UNESP, São Paulo, Brazil.
Mariana PacchioniDepartment of Anesthesiology, Botucatu Medical School, Sao Paulo State University-UNESP, São Paulo, Brazil.ORCID 0000-0003-2006-6018
Julia B CuryDepartment of Anesthesiology, Botucatu Medical School, Sao Paulo State University-UNESP, São Paulo, Brazil.
Iva B SoaresDepartment of Anesthesiology, Botucatu Medical School, Sao Paulo State University-UNESP, São Paulo, Brazil.ORCID 0000-0002-2076-8127
Mariana G BrazDepartment of Anesthesiology, Botucatu Medical School, Sao Paulo State University-UNESP, São Paulo, Brazil.ORCID 0000-0003-4413-226X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionStudies have shown that both perioperative and anesthesia-related cardiac arrest (CA) and mortality rates are much higher in developing countries than in developed countries. This review aimed to compare the rates of perioperative and anesthesia-related CA and mortality during 2 time periods in Brazil.

methodsA systematic review with meta-analysis of full-text Brazilian observational studies was conducted by searching the Medline, EMBASE, LILACS and SciELO databases up to January 29, 2020. The primary outcomes were perioperative CA and mortality rates and the secondary outcomes included anesthesia-related CA and mortality events rates up to 48 postoperative hours.

resultsEleven studies including 719,273 anesthetic procedures, 962 perioperative CAs, 134 anesthesia-related CAs, 1,239 perioperative deaths and 29 anesthesia-related deaths were included. The event rates were evaluated in 2 time periods: pre-1990 and 1990-2020. Perioperative CA rates (per 10,000 anesthetics) decreased from 39.87 (95% confidence interval [CI]: 34.60-45.50) before 1990 to 17.61 (95% CI: 9.21-28.68) in 1990-2020 (P < 0.0001), while the perioperative mortality rate did not alter (from 19.25 [95% CI: 15.64-23.24] pre-1990 to 25.40 [95% CI: 13.01-41.86] in 1990-2020; P = 0.1984). Simultaneously, the anesthesia-related CA rate decreased from 14.39 (95% CI: 11.29-17.86) to 3.90 (95% CI: 2.93-5.01; P < 0.0001), while there was no significant difference in the anesthesia-related mortality rate (from 1.75 [95% CI: 0.76-3.11] to 0.67 [95% CI: 0.09-1.66; P = 0.5404).

conclusionsThis review demonstrates an important reduction in the perioperative CA rate over time in Brazil, with a large and consistent decrease in the anesthesia-related CA rate; however, there were no significant differences in perioperative and anesthesia-related mortality rates between the assessed time periods.

Indexed as

AnesthesiaBrazilHeart ArrestHumansPerioperative PeriodSurvival Rate

Identifiers

PMID33137159
PMCPMC7605701

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.