Evidence map›Paper›PMID 33137145›Full record

ArticlePloS one2020

Electronic cigarette use and subjective cognitive complaints in adults.

Zidian Xie, Deborah J Ossip, Irfan Rahman, Richard J O'Connor, Dongmei Li

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Memory under siege: the cognitive costs of smoking and vaping.Brain, behavior, & immunity - health · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Potential Impact of FDA Flavor Enforcement Policy on Vaping Behavior on Twitter.International journal of environmental research and public health · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zidian XieDepartment of Clinical & Translational Research, University of Rochester Medical Center, Rochester, New York, United States of America.ORCID 0000-0002-5149-7710
Deborah J OssipDepartment of Public Health Sciences, University of Rochester Medical Center, Rochester, New York, United States of America.
Irfan RahmanDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, New York, United States of America.
Richard J O'ConnorDepartment of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, New York, United States of America.
Dongmei LiDepartment of Clinical & Translational Research, University of Rochester Medical Center, Rochester, New York, United States of America.ORCID 0000-0001-9140-2483
University of Rochester Medical Center · USRoswell Park Comprehensive Cancer Center · US

Funding

WNY Center for Research on Flavored Tobacco Products (CRoFT)U54CA228110 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI OSSIP, DEBORAH J · 2018 to 2022
$19.8M
NCI NIH HHS U54 CA228110
6 · The paper itself

Abstract

introductionElectronic cigarette use (vaping) has become popular in recent years. The number of Americans with a variety of cognitive deficits has been increasing dramatically. This study aimed to examine the potential association of vaping with subjective cognitive complaints in US adults.

methodsA combined 2016 and 2017 Behavioral Risk Factor Surveillance System (BRFSS) national survey dataset yielded 886,603 adults who indicated their smoking and vaping status, as well as whether they had subjective cognitive complaints. With this dataset, the cross-sectional association of electronic cigarette use with subjective cognitive complaints was examined using multivariable weighted logistic regression models.

resultsBoth dual users (adjusted Odds Ratio [aOR] = 2.07; 95% Confidence Interval [CI] = 1.66 to 2.60) and current vapers who were either ex-smokers (aOR = 1.94; 95% CI = 1.40 to 2.71) or never smoked (aOR = 1.96; 95% CI = 1.16 to 3.30) showed a significantly higher association with subjective cognitive complaints than never users. Current smokers (aOR = 1.49; 95% CI = 1.32 to 1.69) and ex-smokers (aOR = 1.25; 95% CI = 1.11 to 1.41) had a significantly higher association with subjective cognitive complaints compared to never users. Compared to current smokers, the ex-smokers showed a lower association with subjective cognitive complaints (aOR = 0.84; 95% CI = 0.73 to 0.96). Finally, the association of vaping with subjective cognitive complaints was not statistically significant in individual age group.

conclusionSimilar to smoking, vaping is associated with subjective cognitive complaints in US adults. These results provide preliminary evidence for a cross-sectional association of vaping with potential cognitive health effects in adults.

Indexed as

CognitionAdolescentAdultAgedCognition DisordersDiagnostic Self EvaluationFemaleHumansMaleMiddle AgedVaping

Identifiers

PMID33137145
PMCPMC7605645
OpenAlexW3095067352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.