Trial reportPloS one2020
IMARA: A mother-daughter group randomized controlled trial to reduce sexually transmitted infections in Black/African-American adolescents.
Trial report in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multilevel Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women
Zambian Informed Motivated Aware Responsible Adolescent Girls and Adults
Who cites it
28 citing papers in PubMed, 39 citations in OpenAlex.
- Assessing Differences in mHealth Usability and App Experiences Among Young African American Women: Secondary Analysis of a Randomized Controlled Trial.JMIR human factors · 2024Trial
- Mental health outcomes of a pilot 2-arm randomized controlled trial of a HIV-prevention program for South African adolescent girls and young women and their female caregivers.BMC public health · 2021Trial
- Changes in externalizing and internalizing symptoms among African American female adolescents over 1 year following a mother-daughter sexual health intervention.Journal of consulting and clinical psychology · 2020Trial
- Protective Relationships, Adultification, and Sexual Risk Among Black Adolescent Girls: Examining Maternal, Paternal, Peer, and Community Influences.International journal of environmental research and public health · 2026Article
- Using the Framework for Reporting Adaptation and Modifications-Expanded (FRAME) to Adapt an Evidence-Based HIV-Prevention Intervention for Zambian Adolescent Girls and Young Women.AIDS and behavior · 2026Article
- Navigating an STI diagnosis: The role of social support, intergenerational learning, and transformative growth among Black women.American journal of community psychology · 2026Article
- Addressing Substance Use Disorders Among System-Involved Girls.Child and adolescent psychiatric clinics of North America · 2026Review
- Effects of female caregiver communication and behavior on sexual behavior of South African adolescent girls and young women post-HIV/STI intervention.Children and youth services review · 2025Article
- A hybrid effectiveness implementation trial testing an HIV and STI prevention program for mother figures and their adolescent girls and young women delivered by peer leaders: ZAIMARA study protocol.BMC public health · 2025Article
- Sexually Transmitted Infection (STI) Incidence and Risk Factors Among People with HIV (PWH): Insights from a 13-Year Cohort Study in South Carolina.AIDS and behavior · 2025Article
- Pilot optimization trial of a sexual and reproductive health program for Latina teens and their female caregivers: A study protocol.Contemporary clinical trials communications · 2025Article
- Theater testing a sexual and reproductive health program for Latina teens and their female caregivers: a mixed methods study.BMC public health · 2025Article
- Preparing to implement Floreciendo with Latina teens and their female caregivers: Integrating implementation science and the multiphase optimization strategy framework.Translational behavioral medicine · 2025Article
- Adapting a sexual and reproductive health program for Latina teens and their female caregivers: a qualitative study.Frontiers in public health · 2025Article
- Implementation outcomes of the IMARA-South Africa mother-daughter HIV/STI prevention intervention: A mixed-methods study.Journal of clinical and translational science · 2025Article
- Article
- Developing and assessing a kin keeping scale with application to identifying central influencers in African American family networks.Journal of community genetics · 2023Article
- Cultural interventions addressing disparities in the HIV prevention and treatment cascade among Black/African Americans: a scoping review.BMC public health · 2023Article
- Application of ADAPT-ITT: adapting an evidence-based HIV/STI mother-daughter prevention intervention for Black male caregivers and girls.BMC public health · 2023Article
- Family-Related Factors and HIV-Related Outcomes Among Black Young Men Who Have Sex with Men in Mississippi.AIDS and behavior · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Black/African-American girls are infected with sexually transmitted infections (STIs) at higher rates than their White counterparts. This study tested the efficacy of IMARA, a mother-daughter psychosocial STI/HIV prevention program, on adolescent Black/African-American girls' incident STIs at 12 months in a 2-arm group randomized controlled trial. Black/African-American girls 14-18 years old and their primary female caregiver were eligible for the study. Girls provided urine samples to test for N. gonorrhoeae, C. trachomatis, and T. vaginalis infection at baseline and 12-months. Mother-daughter dyads were randomly assigned to IMARA (n = 118) or a time-matched health promotion control program (n = 81). Retention at 12-months was 86% with no difference across arms. Both interventions were delivered over two consecutive Saturdays totaling 12 hours. Girls who received IMARA were 43% less likely to contract a new STI in the 12-month post-intervention period compared with those in the health promotion control program (p = .011). A secondary follow-up intent-to-treat analysis provided additional support for the protective effect of IMARA, albeit with a similar magnitude of 37% (p = .014). Findings provide early evidence for IMARA's efficacy, such that IMARA protected against STIs at 12-months among adolescent Black/African-American girls. Future research should examine the mechanisms associated with reduced STIs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.