Evidence map›Paper›PMID 33137021›Full record

Observational studyJournal of glaucoma2021

Nocturnal Variability of Intraocular Pressure Monitored With Contact Lens Sensor Is Associated With Visual Field Loss in Glaucoma.

Zhiyong Yang, Kaweh Mansouri, Sasan Moghimi, Robert N Weinreb

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of glaucoma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Using 24-h intraocular pressure-related patterns to identify open-angle glaucoma in thyroid eye disease.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zhiyong YangViterbi Family Department of Ophthalmology and the Shiley Eye Institute, Hamilton Glaucoma Center, University of California, San Diego, La Jolla, CA.
Kaweh MansouriGlaucoma Research Center, Montchoisi Clinic, Swiss Visio, Lausanne, Switzerland.
Sasan MoghimiViterbi Family Department of Ophthalmology and the Shiley Eye Institute, Hamilton Glaucoma Center, University of California, San Diego, La Jolla, CA.
Robert N WeinrebViterbi Family Department of Ophthalmology and the Shiley Eye Institute, Hamilton Glaucoma Center, University of California, San Diego, La Jolla, CA.
University of California, San Diego · USUniversity of Colorado Denver · US

Funding

Vision BiostatisticsP30EY022589 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LINDA M ZANGWILL · 2012 to 2026
$10.3M
Translational Vision Research Training at UCSDT32EY026590 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ZANGWILL, LINDA M · 2016 to 2025
$854k
NEI NIH HHS P30 EY022589NEI NIH HHS T32 EY026590
6 · The paper itself

Abstract

purposeThe aim was to determine whether 24-hour recording of intraocular pressure (IOP)-related ocular dimensional changes with a contact lens sensor (CLS, Triggerfish) is associated with the rate of visual field (VF) progression in primary open-angle glaucoma (POAG) patients.

designThis was a retrospective, observational cohort study.

participantsPatients with POAG were included from the Glaucoma Clinic and Diagnostic Innovations in Glaucoma Study at the Hamilton Glaucoma Center at University of California, San Diego.

methodsA session of 24-hour CLS recording was acquired for 1 eye from each patient. The mean follow-up time was 9.9±4.0 years. The association between CLS variables and rate of change of mean deviation was determined by univariate and multivariate mixed linear regression models.

resultsThirty-two patients, aged 69.8±13.6 years were included, 50% were female. An average of 11.6±5.6 standard automated perimetry examinations was available with a mean rate of mean deviation progression of -0.2±0.4 dB/year. Mean IOP was 17.8±4.2 mm Hg. The mean number of IOP-lowering medications were 1.2±1.0. Each 10-unit larger nocturnal variability of IOP-related ocular dimensional changes measured by CLS recording was significantly associated with -0.25±0.11 dB faster VF loss in POAG patients (P=0.035).

conclusionsTwenty-four-hour CLS recording of IOP-related ocular dimensional change was associated with faster VF progression. Such CLS recordings are useful to assess the risk of in progression in POAG patients.

Indexed as

Contact LensesGlaucomaGlaucoma, Open-AngleCircadian RhythmCohort StudiesDisease ProgressionFemaleHumansIntraocular PressureTonometry, OcularVisual FieldsVisual Field Tests

Identifiers

PMID33137021
PMCPMC7987586
OpenAlexW3095449876

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.