ArticleAging2020
Development and validation of prognostic nomogram for germ cell testicular cancer patients.
Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Prognostic Nomograms and Scoring System: Novel Approaches to Forecast Overall Survival and Cancer-Specific Survival in Patients With Testicular Cancer.Cancer medicine · 2026Observational
- Comparing oncologic outcomes of partial and radical nephrectomy for T2 renal cell carcinoma: a propensity score matching cohort study and an external multicenter validation.World journal of urology · 2025Article
- Development and validation of a prognostic nomogram for patients with ganglioneuroblastoma: A SEER-based study.Heliyon · 2024Article
- Nomogram for predicting testicular yolk sac tumor in children based on age, alpha-fetoprotein, and ultrasonography.Frontiers in pediatrics · 2024Article
- Differences in future life expectancy of testicular germ-cell tumor patients vs. age-matched male population-based controls.International urology and nephrology · 2023Article
- Development and validation of a nomogram to predict lung metastasis in patients with testicular germ cell tumors.Heliyon · 2023Article
- Construction of the XGBoost model for early lung cancer prediction based on metabolic indices.BMC medical informatics and decision making · 2023Article
- Clinical features and prognostic factors in patients diagnosed with lymphovascular invasion of testicular germ-cell tumors: Analysis based on the SEER database.Frontiers in oncology · 2023Article
- Characteristics of lung metastasis in testicular cancer: A large-scale population analysis based on propensity score matching.Frontiers in surgery · 2022Article
- Identification of prognostic factors for predicting survival of patients with malignant adrenal tumors: A population-based study.Frontiers in oncology · 2022Article
- Development and validation of prognostic nomogram for lung cancer patients below the age of 45 years.Bosnian journal of basic medical sciences · 2021Article
- A Population-Based Study: How to Identify High-Risk T1-2 Esophageal Cancer Patients?Frontiers in oncology · 2021Article
- Overall Survival Analyses following Adjuvant Chemotherapy or Nonadjuvant Chemotherapy in Patients with Stage IB Non-Small-Cell Lung Cancer.Journal of oncology · 2021Article
- Development and Validation of Prognostic Nomograms for Lung Squamous Cell Carcinoma With Brain Metastasis in Patients Aged 45 Years or Older: A Population-Based Study.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of our study was to establish a reliable and practical nomogram based on significant clinical factors to predict the overall survival (OS) and cancer-specific survival (CSS) of patients with germ cell testicular cancer (GCTC). Patients diagnosed with GCTC between 2004 and 2015 were obtained from the SEER database. Nomograms were constructed using the R software to predict the OS and CSS probabilities and the constructed nomograms were validated and calibrated. A total of 22,165 GCTC patients were enrolled in the study, including the training cohort (15,515 patients) and the validation cohort (6,650 patients). In the training cohort, multivariate Cox regression showed that age, race, AJCC stage, SEER stage and surgery were independent prognostic factors for OS, while age, race, AJCC stage, TM stage, SEER stage and radiotherapy were independent prognostic factors for CSS. Based on the above Cox regression results, we constructed prognostic nomograms of OS and CSS in GCTC patients and found that the OS nomograms had higher C-index and AUC compared to TNM stage in the training and validation cohorts. In addition, in the training and external validation cohorts, the calibration curves showed a good consistency between the predicted and actual 3-, 5- and 10-year OS and CSS rates of the nomogram. The current prognostic nomogram can provide a personalized risk assessment for the survival of GCTC patients.
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