Evidence map›Paper›PMID 33136399›Full record

ArticleJournal of natural products2020

Discovery of a Remarkable Methyl Shift Effect in the Vanilloid Activity of Triterpene Amides.

Rosa Maria Vitale, Cristina Avonto, Danilo Del Prete, Aniello Schiano Moriello, Pietro Amodeo, Giovanni Appendino, Luciano De Petrocellis

Abstract read
In one paragraph

Article in Journal of natural products, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Tigliane Diterpenoids.Progress in the chemistry of organic natural products · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rosa Maria VitaleInstitute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy.ORCID 0000-0001-9243-1307
Cristina AvontoNational Center for Natural Products Research, Research Institute of Pharmaceutical Science, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, United States.
Danilo Del PreteDipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.ORCID 0000-0002-2161-8980
Aniello Schiano MorielloEndocannabinoid Research Group (ERG), Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy.
Pietro AmodeoInstitute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy.ORCID 0000-0002-6439-7575
Giovanni AppendinoDipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.ORCID 0000-0002-4170-9919
Luciano De PetrocellisEndocannabinoid Research Group (ERG), Institute of Biomolecular Chemistry, National Research Council (ICB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As part of a study on triterpenoid conjugates, the dietary pentacyclic triterpenoids oleanolic (

Indexed as

Drug DiscoveryAmidesHEK293 CellsHumansMolecular Docking SimulationTriterpenesTRPV Cation ChannelsAmidesTriterpenesTRPV1 receptorTRPV Cation Channels

Identifiers

PMID33136399
PMCPMC8016363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.