Evidence map›Paper›PMID 33136372›Full record

ArticleBiochemistry2020

Juliel Espinosa, Ti-Yu Lin, Yadyvic Estrella, Byungchul Kim, Henrik Molina, Howard C Hang

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Recombinant AttenuatedBiomolecules · 2026
    Article
  3. Article
  4. Frontiers in immunology · 2026
    Review
  5. Journal of bacteriology · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Secreted antigen A peptidoglycan hydrolase is essential forbioRxiv : the preprint server for biology · 2024
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Juliel EspinosaLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.ORCID 0000-0003-2104-5331
Ti-Yu LinLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.
Yadyvic EstrellaLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.
Byungchul KimLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.
Henrik MolinaProteomics Resource Center, The Rockefeller University, New York, New York 10065, United States.
Howard C HangLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.ORCID 0000-0003-4053-5547
Rockefeller University · USScripps Institution of Oceanography · US

Funding

Immunity and Infectious DiseaseT32AI070084 · NIAID · ROCKEFELLER UNIVERSITY · PI Michel C Nussenzweig · 2008 to 2026
$3.3M
Elucidation of Commensal Bacteria Mechanisms Required for Host ProtectionR01GM103593 · NIGMS · ROCKEFELLER UNIVERSITY · PI HANG, HOWARD C · 2013 to 2020
$2.8M
Translation of commensal bacteria mechanism for immunotherapyR01CA245292 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI HANG, HOWARD C · 2020 to 2024
$2.7M
Distal gut microbiome targets of host anti-proteolytic proteins during colitisR21AI156674 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI HANG, HOWARD C · 2021 to 2022
$488k
NCI NIH HHS R01 CA245292NIAID NIH HHS R21 AI156674NIAID NIH HHS T32 AI070084NIGMS NIH HHS R01 GM103593
6 · The paper itself

Abstract

Peptidoglycan is a vital component of the bacterial cell wall, and its dynamic remodeling by NlpC/p60 hydrolases is crucial for proper cell division and survival. Beyond these essential functions, we previously discovered that

Indexed as

Bacterial ProteinsCatalytic DomainCell DivisionEnterococcusMicroscopy, Electron, TransmissionMicroscopy, FluorescenceMolecular Docking SimulationMutagenesis, Site-DirectedN-Acetylmuramoyl-L-alanine AmidasePeptidoglycanSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationStructure-Activity RelationshipBacterial ProteinsN-Acetylmuramoyl-L-alanine AmidasePeptidoglycan

Identifiers

PMID33136372
PMCPMC8191637
OpenAlexW3095242996

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.