ArticleInternational journal of clinical pharmacy2021
Development of medication regimen complexity index: Japanese version and application in elderly patients.
Article in International journal of clinical pharmacy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Association between medication regimen complexity and glycemic control among patients with type 2 diabetes.Journal of the American Pharmacists Association : JAPhATrial
- Reducing medication burden and improving pressure injury outcomes in older emergency patients: a pharmacist-nurse collaboration.Frontiers in medicine · 2026Article
- Evaluation of the efficacy of aromatherapy and complementary yoga on indicators of medication regimen complexity: A retrospective study.BMC complementary medicine and therapies · 2025Observational
- Identifying characteristics of patients requiring proactive pharmaceutical interventions in the recovery period and assessing the effect of rehabilitation and drugs: a retrospective study.Journal of pharmaceutical health care and sciences · 2025Article
- Association of medication regimen complexity index with ADRs in HIV/AIDS patients: a retrospective cohort study.Frontiers in pharmacology · 2025Article
- Statement on medication simplification in long-term care facilities by the Japanese Society of Geriatric Pharmacy: English translation of the Japanese article.Geriatrics & gerontology international · 2025Review
- Analysis of Various Factors Associated With Opioid Dose Escalation in Patients With Cancer Pain.Cureus · 2022Article
- Evaluation of changes in prescription among Japanese elderly patients before and after transition to home care.Journal of general and family medicine · 2022Article
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Authors and funding
8 authors at 2 institutions in 1 country.
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Abstract
Background Medication regimen complexity includes various aspects of a regimen, including the dosage form, number of medications and need for additional information for use. Complicated medication regimens cause non-adherence to prescribed medications, making it essential to evaluate medication regimen complexity in older adults to improve adherence to prescribed medications and clinical outcomes. The medication regimen complexity index is currently the most widely used scale for quantifying regimen complexity; however, it has yet to be adopted in Japan. Objective This study aimed to translate the medication regimen complexity index to Japanese and assess its reliability and validity for application in elderly patients in Japan. Setting This study was conducted in a clinic that provides home medical care to patients in the southern part of Ibaraki prefecture, Japan. Method The validation process consisted of translation of the original English version of the medication regimen complexity index to Japanese followed by back-translation to English, comparison of the back-translated and original versions, pilot testing, and assessment of the Japanese version by two raters using the medication regimens of 72 patients with chronic diseases. Main outcome measure The psychometric properties of the index were evaluated according to inter-rater and test-retest reliability, and convergent and discriminant validity. Results The mean age of the 72 patients was 84.3 years. The scale showed high inter-rater reliability (intraclass correlation coefficient 0.946) and test-retest reliability (intraclass correlation coefficient 0.991) for total scores. The number of medications was positively correlated with total medication regimen complexity index score (r
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