Evidence map›Paper›PMID 33136228›Full record

ArticleDigestive diseases and sciences2021

Frailty Does Not Impact Caregiver Burden in Patients with Cirrhosis.

Elizabeth S Aby, Nguyen V Pham, Jung J Yum, Tien S Dong, Hussein Ghasham, Fatima Bedier, Claire Malley, Joanna Schaenman, Sammy Saab

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In one paragraph

Article in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Elizabeth S AbyDepartments of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Nguyen V PhamDepartments of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Jung J YumDepartments of Surgery, University of California at Los Angeles, Los Angeles, CA, USA.
Tien S DongDepartments of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Hussein GhashamDepartments of Surgery, University of California at Los Angeles, Los Angeles, CA, USA.
Fatima BedierDepartments of Surgery, University of California at Los Angeles, Los Angeles, CA, USA.
Claire MalleyDepartments of Surgery, University of California at Los Angeles, Los Angeles, CA, USA.
Joanna SchaenmanDepartments of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Sammy SaabDepartments of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. SSaab@mednet.ucla.edu.
University of California, Los Angeles · USUCLA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFrailty is common and is associated with increased mortality, lower quality of life, and higher readmission rates in cirrhotic patients. Not only are these outcomes important, but further understanding the impact of frailty on a caregiver's life is crucial to better comprehend caregiver burden in cirrhotic patients and develop strategies to improve care for patients and their caregivers.

methodsA single-center, prospective study was conducted of cirrhotic patients and their caregivers between 4/1/2019 and 11/1/2019. Frailty testing combined aspects from the Fried Frailty Instrument, Short Physical Performance Battery, and activities of daily living. Caregivers completed questionnaires to evaluate caregiver burden using the Zarit Burden Interview (ZBI-12), and perceived social support, using the Interpersonal Support Evaluation List.

resultsIn total, 94 cirrhotic patients were included, 50% males with a median age of 63.1 years. The most common etiology of cirrhosis was nonalcoholic steatohepatitis. Frailty was prevalent (45.1%). In total, 12.8% of caregivers reported a high burden based on ZBI-12. There was no association between frailty and caregiver burden, hospitalization rates, or death. However, frailty was associated with a higher number of outpatient GI visits (p = 0.002). Lower perceived social support among caregivers was associated with a higher caregiver burden (p < 0.0001).

conclusionFrailty is prevalent in cirrhotic patients but is not associated with higher rates of caregiver burden. Low perceived social support among caregivers, however, was associated with higher caregiver burden. It is important to recognize the impact of caregiver burden on caregivers of cirrhotic patients and ensure caregivers have the appropriate support to mitigate burden.

Indexed as

Caregiver BurdenAgedFemaleFrailtyHumansLiver CirrhosisMaleMiddle AgedProspective StudiesSocioeconomic FactorsSurveys and QuestionnairesCaregiver burdenCirrhosisFrailty

Identifiers

PMID33136228
OpenAlexW3097874263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.