Evidence map›Paper›PMID 33135952›Full record

ArticleJournal of biological rhythms2021

Photoreceptor Degeneration in Homozygous Male Per2

Varunika Goyal, Christopher DeVera, Kenkichi Baba, Jana Sellers, Micah A Chrenek, P Michael Iuvone, Gianluca Tosini

Open access · hybridAbstract read
In one paragraph

Article in Journal of biological rhythms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cell-Type-Specific Circadian Bioluminescence Rhythms inJournal of biological rhythms · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Varunika GoyalNeuroscience Institute, Department of Pharmacology & Toxicology, Morehouse School of Medicine, Atlanta, Georgia.
Christopher DeVeraNeuroscience Institute, Department of Pharmacology & Toxicology, Morehouse School of Medicine, Atlanta, Georgia.ORCID 0000-0003-3965-7061
Kenkichi BabaNeuroscience Institute, Department of Pharmacology & Toxicology, Morehouse School of Medicine, Atlanta, Georgia.
Jana SellersDepartment of Ophthalmology, Emory Eye Center, Emory University, Atlanta, Georgia.
Micah A ChrenekDepartment of Ophthalmology, Emory Eye Center, Emory University, Atlanta, Georgia.ORCID 0000-0002-1366-5963
P Michael IuvoneDepartment of Ophthalmology, Emory Eye Center, Emory University, Atlanta, Georgia.
Gianluca TosiniNeuroscience Institute, Department of Pharmacology & Toxicology, Morehouse School of Medicine, Atlanta, Georgia.ORCID 0000-0003-3645-4533
Emory University · USMorehouse School of Medicine · US

Funding

P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI BOATRIGHT, JEFFREY H · 1986 to 2025
$15.3M
Program Evaluation - Internal & External U54NS083932 · NINDS · MOREHOUSE SCHOOL OF MEDICINE · PI MACLEISH, PETER RAYMOND · 2013 to 2017
$7.7M
Neuromodulators and Circadian Clocks: Roles in Retinal Function and DysfunctionR01EY004864 · NEI · EMORY UNIVERSITY · PI IUVONE, P MICHAEL · 1985 to 2018
$7.0M
Circadian regulation of RPE functionsR01EY026291 · NEI · MOREHOUSE SCHOOL OF MEDICINE · PI TOSINI, GIANLUCA · 2016 to 2020
$2.1M
Regulation of eye development by an Opsin5-dopamine pathwayR01EY027711 · NEI · EMORY UNIVERSITY · PI IUVONE, P MICHAEL, LANG, RICHARD A. · 2017 to 2020
$1.9M
Light regulated vascular development in the eye via the Hippo pathwayR01EY032029 · NEI · CINCINNATI CHILDRENS HOSP MED CTR · PI LANG, RICHARD A., XIN, MEI · 2021 to 2024
$1.6M
Retinal Circadian Rhythms and Photoreceptors ViabilitySC2GM116760 · NIGMS · MOREHOUSE SCHOOL OF MEDICINE · PI BABA, KENKICHI · 2016 to 2018
$426k
NEI NIH HHS P30 EY006360NEI NIH HHS R01 EY004864NEI NIH HHS R01 EY026291NEI NIH HHS R01 EY027711NEI NIH HHS R01 EY032029NIGMS NIH HHS SC2 GM116760NINDS NIH HHS U54 NS083932
6 · The paper itself

Abstract

The Per2

Indexed as

Circadian RhythmHomozygoteRetinal DegenerationAgingAnimalsElectroretinographyMaleMiceMice, Inbred C57BLModels, AnimalPeriod Circadian ProteinsRetinal Pigment EpitheliumPer2 protein, mousePeriod Circadian ProteinsagingcircadianmicePer2lucphotoreceptorsretinal pigment epithelium

Identifiers

PMID33135952
PMCPMC8722430
OpenAlexW3096814185

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.