Evidence map›Paper›PMID 33135780›Full record

SynthesisJournal of the American Geriatrics Society2021

Detecting Delirium: A Systematic Review of Identification Instruments for Non-ICU Settings.

Benjamin K I Helfand, Madeline L D'Aquila, Patricia Tabloski, Kristen Erickson, Jirong Yue, Tamara G Fong, Tammy T Hshieh, Eran D Metzger, Eva M Schmitt, Edwin D Boudreaux and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Delirium among older adults living at home: a systematic review of prevalence, incidence, and risk factors.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Pooled it
  3. Trial
  4. Video-based Detection of Delirium in Hospitalized Adults.medRxiv : the preprint server for health sciences · 2026
    Article
  5. Article
  6. Observational
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Harmonization of Four Delirium Instruments: Creating Crosswalks and the Delirium Item-Bank (DEL-IB).The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Benjamin K I HelfandDepartment of Emergency Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0002-3651-3372
Madeline L D'AquilaAging Brain Center, Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts, USA.
Patricia TabloskiWilliam F. Connell School of Nursing, Boston College, Boston, Massachusetts, USA.
Kristen EricksonAging Brain Center, Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts, USA.
Jirong YueDepartment of Geriatrics, West China Hospital, Sichuan University, Chengdu, China.
Tamara G FongAging Brain Center, Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts, USA.
Tammy T HshiehAging Brain Center, Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts, USA.
Eran D MetzgerDepartment of Psychiatry, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Eva M SchmittAging Brain Center, Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts, USA.
Edwin D BoudreauxDepartment of Emergency Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Sharon K InouyeAging Brain Center, Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts, USA.
Richard N JonesDepartments of Psychiatry and Human Behavior and Neurology, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.

Funding

The Role of Inflammation in the Pathophysiology of Delirium and its Associated Long-Term Cognitive DeclineP01AG031720 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K. · 2010 to 2022
$26.7M
Development and Validation of a Delirium Severity ToolkitR01AG044518 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K., JONES, RICHARD N · 2014 to 2024
$7.3M
Medical Scientist Training at UMMS Administrative SupplementT32GM107000 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIEFE, CATARINA I. · 2013 to 2022
$4.9M
Supplement to Network for Investigation of Delirium across the U.S (NIDUS)R24AG054259 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K. · 2016 to 2020
$4.3M
Measurement in Health: Advancing Assessment of DeliriumR36AG070184 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HELFAND, BENJAMIN · 2021 to 2021
$64k
NIA NIH HHS P01 AG031720NIA NIH HHS P01AG031720NIA NIH HHS R01 AG044518NIA NIH HHS R01AG044518NIA NIH HHS R24 AG054259NIA NIH HHS R24AG054259NIA NIH HHS R36 AG070184NIGMS NIH HHS T32 GM107000NIGMS NIH HHS T32GM107000
6 · The paper itself

Abstract

BACKGROUND/

objectivesDelirium manifests clinically in varying ways across settings. More than 40 instruments currently exist for characterizing the different manifestations of delirium. We evaluated all delirium identification instruments according to their psychometric properties and frequency of citation in published research.

designWe conducted the systematic review by searching Cumulative Index to Nursing and Allied Health Literature (CINAHL), Cochrane Library, Excerpta Medica Database (Embase), PsycINFO, PubMed, and Web of Science from January 1, 1974, to January 31, 2020, with the keywords "delirium" and "instruments," along with their known synonyms. We selected only systematic reviews, meta-analyses, or narrative literature reviews including multiple delirium identification instruments. MEASUREMENTS: Two reviewers assessed the eligibility of articles and extracted data on all potential delirium identification instruments. Using the original publication on each instrument, the psychometric properties were examined using the Consensus-based Standards for the Selection of Health Measurement Instruments (COSMIN) framework.

resultsOf 2,542 articles identified, 75 met eligibility criteria, yielding 30 different delirium identification instruments. A count of citations was determined using Scopus for the original publication for each instrument. Each instrument underwent methodological quality review of psychometric properties using COSMIN definitions. An expert panel categorized key domains for delirium identification based on criteria from the Diagnostic and Statistical Manual of Mental Disorders (DSM)-III through DSM-5. Four instruments were notable for having at least two of three of the following: citation count of 200 or more, strong validation methodology in their original publication, and fulfillment of DSM-5 criteria. These were, alphabetically, Confusion Assessment Method, Delirium Observation Screening Scale, Delirium Rating Scale-Revised-98, and Memorial Delirium Assessment Scale.

conclusionFour commonly used and well-validated instruments can be recommended for clinical and research use. An important area for future investigation is to harmonize these measures to compare and combine studies on delirium.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersPsychiatric Status Rating ScalesAgedDeliriumHumansPsychometricsReproducibility of Resultsdeliriummeasurementpsychometricssystematic review

Identifiers

PMID33135780
PMCPMC7902461

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.