Evidence map›Paper›PMID 33135480›Full record

ArticleAmerican journal of physiology. Renal physiology2021

A uropathogenic

Hannah Ruetten, Jaskiran Sandhu, Brett Mueller, Peiqing Wang, Helen L Zhang, Kyle A Wegner, Mark Cadena, Simran Sandhu, Lisa L Abler, Jonathan Zhu and 7 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Macrophages and TGFB signaling regulate fibrosis in theAmerican journal of physiology. Renal physiology · 2026
    Article
  3. Mechanisms of prostatic inflammation-mediated male lower urinary tract symptoms.American journal of clinical and experimental urology · 2025
    Review
  4. Article
  5. Article
  6. Real-Time Void Spot Assay.Journal of visualized experiments : JoVE · 2023
    Article
  7. The impact of short term, long term and intermittentAmerican journal of clinical and experimental urology · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Osteopontin Deficiency Ameliorates Prostatic Fibrosis and Inflammation.International journal of molecular sciences · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. A uropathogenicAmerican journal of physiology. Renal physiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Hannah RuettenDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.ORCID 0000-0001-6263-6221
Jaskiran SandhuDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
Brett MuellerDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
Peiqing WangDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
Helen L ZhangDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
Kyle A WegnerUniversity of Wisconsin-Madison/UMASS Boston George M. O'Brien Center for Benign Urologic Research, Madison, Wisconsin, and Boston, Massachusetts.
Mark CadenaDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
Simran SandhuDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
Lisa L AblerDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
Jonathan ZhuDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
Chelsea A O'DriscollDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
Britta ChelgrenDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
Zunyi WangUniversity of Wisconsin-Madison/UMASS Boston George M. O'Brien Center for Benign Urologic Research, Madison, Wisconsin, and Boston, Massachusetts.
Tian ShenColumbia University, Department of Medicine, New York, New York.
Jonathan BaraschColumbia University, Department of Medicine, New York, New York.
Dale E BjorlingUniversity of Wisconsin-Madison/UMASS Boston George M. O'Brien Center for Benign Urologic Research, Madison, Wisconsin, and Boston, Massachusetts.
Chad M VezinaDepartment of Comparative Biosciences, University of Wisconsin-Madison, Madison, Wisconsin.
University of Wisconsin–Madison · USColumbia University · US

Funding

Transcriptional Regulation of Urothelial Differentiation During Homeostasis and Repair in Response to Urinary Tract InfectionU54DK104309 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JONATHAN M. BARASCH, ALI G GHARAVI · 2014 to 2026
$17.7M
Role of Beta-Catenin in Urinary DysfunctionU54DK104310 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI MACOSKA, JILL A., MARKER, PAUL C · 2014 to 2023
$12.8M
NRSA Training CoreTL1TR002375 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI Vivek Prabhakaran · 2017 to 2026
$8.4M
REPRODUCTIVE AND DEVELOPMENTAL TOXICITY OF DIOXINR01ES001332 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI PETERSON, RICHARD EUGENE, VEZINA, CHAD M. · 1985 to 2021
$5.3M
Role of DNA methylation in prostate glandular development and urinary functionR01DK099328 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI VEZINA, CHAD M. · 2014 to 2018
$1.6M
Prostate inflammation increases collagen and voiding dysfunctionF30DK122686 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI RUETTEN, HANNAH MARGARET · 2019 to 2022
$157k
TCDD Reprograms Prostate Stroma and Causes Fibrosis to Induce Urinary DysfunctionF31ES028594 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI WEGNER, KYLE ALLEN · 2018 to 2019
$54k
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2U54 DK104309-06HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) RO1 DK099328HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) U54 DK104310S1NCATS NIH HHS TL1 TR002375NIDDK NIH HHS F30 DK122686NIDDK NIH HHS R01 DK099328NIDDK NIH HHS U54 DK104309NIDDK NIH HHS U54 DK104310NIEHS NIH HHS F31 ES028594NIEHS NIH HHS R01 ES001332
6 · The paper itself

Abstract

Bacterial infection is one known etiology of prostatic inflammation. Prostatic inflammation is associated with prostatic collagen accumulation and both are linked to progressive lower urinary tract symptoms in men. We characterized a model of prostatic inflammation using transurethral instillations of

Indexed as

ActinsAnimalsCollagen Type ICollagen Type I, alpha 1 ChainDisease Models, AnimalEscherichia coli InfectionsLeukocyte Common AntigensMaleMiceMice, Inbred C57BLProcollagenProstateProstatitisTissue Culture TechniquesUropathogenic Escherichia coliActa2 protein, mouseActinsCollagen Type ICollagen Type I, alpha 1 ChainLeukocyte Common AntigensProcollagenPtprc protein, mousebenign prostatic hyperplasiacollagen type I-α1Escherichia colilower urinary tract symptomsprostatitis

Identifiers

PMID33135480
PMCPMC7847049
OpenAlexW3096432126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.