Evidence map›Paper›PMID 33135401›Full record

ArticleInvestigative and clinical urology2020

Expert-level segmentation using deep learning for volumetry of polycystic kidney and liver.

Tae Young Shin, Hyunsuk Kim, Joong Hyup Lee, Jong Suk Choi, Hyun Seok Min, Hyungjoo Cho, Kyungwook Kim, Geon Kang, Jungkyu Kim, Sieun Yoon and 8 more

Open access · diamondAbstract read
In one paragraph

Article in Investigative and clinical urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  6. Reporting ADPK Disease Phenotypes on Abdominal Scans.Kidney international reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 4 countries.

Tae Young Shin *Synergy A.I. Co.Ltd., Chuncheon, Korea.ORCID 0000-0002-3910-9252
Hyunsuk Kim *Department of Internal Medicine, Division of Nephrology, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.ORCID 0000-0003-1889-253X
Joong Hyup LeeSynergy A.I. Co.Ltd., Chuncheon, Korea.ORCID 0000-0003-3501-0914
Jong Suk ChoiDepartment of Urology, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.ORCID 0000-0002-4406-9195
Hyun Seok MinTomocube, Inc., Daejeon, Korea.ORCID 0000-0002-7435-7884
Hyungjoo ChoTomocube, Inc., Daejeon, Korea.ORCID 0000-0002-3074-8429
Kyungwook KimSchulich School of Medicine & Dentistry, The University of Western, Ontario, London, ON, Canada.ORCID 0000-0002-0279-329X
Geon KangDepartment of Urology, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.ORCID 0000-0001-7203-1699
Jungkyu KimDepartment of Urology, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.
Sieun YoonSchulich School of Medicine & Dentistry, The University of Western, Ontario, London, ON, Canada.ORCID 0000-0001-5315-7050
Hyungyu ParkDepartment of Urology, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.
Yeong Uk HwangDepartment of Radiology, Inje University Ilsan Paik Hospital, Goyang, Korea.ORCID 0000-0002-5056-4141
Hyo Jin KimDepartment of Internal Medicine, Pusan National University Hospital, Busan, Korea.ORCID 0000-0001-9289-9073
Miyeun HanDepartment of Internal Medicine, Pusan National University Hospital, Busan, Korea.ORCID 0000-0001-7304-2496
Eunjin BaeDepartment of Internal Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, Korea.ORCID 0000-0001-6890-4725
Jong Woo YoonDepartment of Internal Medicine, Division of Nephrology, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.ORCID 0000-0002-7915-3733
Koon Ho RhaDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0001-8588-7584
Yong Seong LeeDepartment of Urology, Hallym University Sacred Heart Hospital, Hallym University Collge of Medicine, Anyang, Korea. novavia@hallym.or.kr.ORCID 0000-0003-0611-4554
Sacred Heart Hospital · NGDaejeon University · KRWestern University · CAChangwon National University · KRInje University Ilsan Paik Hospital · KRPusan National University Hospital · KRSacred Heart Hospital · USSynergy Health · USYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVolumetry is used in polycystic kidney and liver diseases (PKLDs), including autosomal dominant polycystic kidney disease (ADPKD), to assess disease progression and drug efficiency. However, since no rapid and accurate method for volumetry has been developed, volumetry has not yet been established in clinical practice, hindering the development of therapies for PKLD. This study presents an artificial intelligence (AI)-based volumetry method for PKLD. MATERIALS AND

methodsThe performance of AI was first evaluated in comparison with ground-truth (GT). We trained a V-net-based convolutional neural network on 175 ADPKD computed tomography (CT) segmentations, which served as the GT and were agreed upon by 3 experts using images from 214 patients analyzed with volumetry. The dice similarity coefficient (DSC), interobserver correlation coefficient (ICC), and Bland-Altman plots of 39 GT and AI segmentations in the validation set were compared. Next, the performance of AI on the segmentation of 50 random CT images was compared with that of 11 PKLD specialists based on the resulting DSC and ICC.

resultsThe DSC and ICC of the AI were 0.961 and 0.999729, respectively. The error rate was within 3% for approximately 95% of the CT scans (error<1%, 46.2%; 1%≤error<3%, 48.7%). Compared with the specialists, AI showed moderate performance. Furthermore, an outlier in our results confirmed that even PKLD specialists can make mistakes in volumetry.

conclusionsPKLD volumetry using AI was fast and accurate. AI performed comparably to human specialists, suggesting its use may be practical in clinical settings.

Indexed as

Deep LearningArtificial IntelligenceCystsHumansLiver DiseasesPolycystic Kidney DiseasesArtificial intelligencePolycystic kidney diseasesTomography

Identifiers

PMID33135401
PMCPMC7606119
OpenAlexW3040599202

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.