ArticleBrain and behavior2020
Functional connectivity in default mode network correlates with severity of hypoxemia in obstructive sleep apnea.
Article in Brain and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Reduced cerebral blood flow in obstructive sleep apnea: A meta-analysis of SPECT and MRI studies.Sleep & breathing = Schlaf & Atmung · 2026Pooled it
- Obstructive sleep apnea and attention deficits: A systematic review of magnetic resonance imaging biomarkers and neuropsychological assessments.Brain and behavior · 2023Pooled it
- Hypoxia's Impact on Hippocampal Functional Connectivity: Insights from Resting-State fMRI Studies.Brain sciences · 2025Review
- Obstructive Sleep Apnea Treatment for Brain Health: Improvement in Connectivity but Not Measurable Function?American journal of respiratory and critical care medicine · 2025Article
- Altered functional network topology and connectivity in female nurses with shift work sleep disorder.Frontiers in systems neuroscience · 2025Article
- Machine Learning Classification Based on Individual Whole-Brain Functional Connectivity in Male OSA Patients.Nature and science of sleep · 2025Article
- Abnormal dynamic functional connectivity and topological properties of cerebellar network in male obstructive sleep apnea.CNS neuroscience & therapeutics · 2024Article
- Functional Connectivity Changes in Amygdala Subregions of Obstructive Sleep Apnea Patients After Six Months of Continuous Positive Airway Pressure Treatment.Nature and science of sleep · 2024Article
- Treatment of hypertension and obstructive sleep apnea counteracts cognitive decline in common neurocognitive disorders in diagnosis-related patterns.Scientific reports · 2023Article
- Functional Connectivity Changes in the Insular Subregions of Patients with Obstructive Sleep Apnea after 6 Months of Continuous Positive Airway Pressure Treatment.Neural plasticity · 2023Article
- Associations among sleep-disordered breathing, arousal response, and risk of mild cognitive impairment in a northern Taiwan population.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Abnormal Functional Connectivity of Hippocampal Subdivisions in Obstructive Sleep Apnea: A Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in neuroscience · 2022Article
- Widespread aberrant functional connectivity throughout the whole brain in obstructive sleep apnea.Frontiers in neuroscience · 2022Article
- Frequency-specific alterations in intrinsic low-frequency oscillations in newly diagnosed male patients with obstructive sleep apnea.Frontiers in neuroscience · 2022Article
- Inherent regional brain activity changes in male obstructive sleep apnea with mild cognitive impairment: A resting-state magnetic resonance study.Frontiers in aging neuroscience · 2022Article
- Functional connectivity in default mode network correlates with severity of hypoxemia in obstructive sleep apnea.Brain and behavior · 2020Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
introductionObstructive sleep apnea (OSA)-associated hypoxemia, sleep fragmentation, and cerebral vascular dysfunction are implicated in cognitive dysfunction. Functional connectivity within default mode network (DMN) is a possible mechanism underlying the cognitive impairment. The aim of this study was to investigate the impact of hypoxemia and sleep fragmentation on functional connectivity and on cognitive performance in patients with OSA.
methodsTwenty-eight patients with OSA were included (mean age = 58.0 ± 8.5 years). We correlated the functional connectivity in DMN with cognitive performances and further analyzed the relationship of functional connectivity in DMN with hypoxemia severity, as revealed by apnea-hypopnea index (AHI), oxygen desaturation index (ODI), and nadir SaO
resultsFunctional connectivity in DMN was associated with AHI, ODI, and nadir SaO
conclusionFunctional connectivity in DMN is implicated in impairment of global cognitive function and of attention in OSA patients. The functional connectivity in the DMN is associated with hypoxemia rather than with sleep fragmentation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.