Evidence map›Paper›PMID 33135274›Full record

ArticleAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2021

Delirium Prevention, Detection, and Treatment in Emergency Medicine Settings: A Geriatric Emergency Care Applied Research (GEAR) Network Scoping Review and Consensus Statement.

Christopher R Carpenter, Nada Hammouda, Elizabeth A Linton, Michelle Doering, Ugochi K Ohuabunwa, Kelly J Ko, William W Hung, Manish N Shah, Lee A Lindquist, Kevin Biese and 6 more

Open access · greenAbstract readScoping ReviewConsensus Statement
In one paragraph

Article in Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 6 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 6 syntheses or guidelines pooled it, 100 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Risk factors and risk stratification approaches for delirium screening: A Geriatric Emergency Department Guidelines 2.0 systematic review.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2024
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Effects of a Geriatric Emergency Department Multidisciplinary Intervention on Functional Status and Quality of Life: A Pre/Post Cohort Study.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Trial
  8. Trial
  9. Review
  10. Article
  11. Review
  12. Article
  13. Beyond Triage: Cognitive Profiles and ED-To-Inpatient Costs and Resource Pathways in Older Adults.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Article
  14. Improving prehospital and emergency care for patients with mental dysregulation: a comprehensive research agenda.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026
    Article
  15. Article
  16. The Geriatric Emergency Care Applied Research Standardization Study (GEARSS): An Observational Study of Older Emergency Department Patients.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Observational
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 1 country.

Christopher R CarpenterFrom the, Department of Emergency Medicine, Washington University in St. Louis School of Medicine, Emergency Care Research Core, St. Louis, MI, USA.ORCID https://orcid.org/0000-0002-2603-7157
Nada Hammoudathe, Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Elizabeth A Lintonthe, Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID https://orcid.org/0000-0002-9558-0858
Michelle Doeringthe, Becker Medical Library, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Ugochi K Ohuabunwathe, Division of General Medicine and Geriatrics, Emory University School of Medicine, Atlanta, GA, USA.
Kelly J KoClinical Research, West Health Institute, La Jolla, CA, USA.
William W HungJames J. Peters VA Medical Center, Bronx, NY, USA.
Manish N Shahthe, BerbeeWalsh Department of Emergency Medicine, University of Wisconsin-Madison, Madison, WI, USA.ORCID https://orcid.org/0000-0001-6331-1074
Lee A Lindquistthe, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Kevin Biesethe, Departments of Emergency Medicine and Internal Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Daniel Weithe, BerbeeWalsh Department of Emergency Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Libby HoyPFCC Partners, Long Beach, CA, USA.
Lori NerbonnePFCC Partners, Long Beach, CA, USA.
Ula Hwangthe, Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA.
Scott M Dresdenand the, Department of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-9250-3320
GEAR Network
Northwestern University · USUniversity of Wisconsin–Madison · USWashington University in St. Louis · USEmory University · USIcahn School of Medicine at Mount Sinai · USJames J. Peters VA Medical Center · USJohns Hopkins University · USUniversity of North Carolina at Chapel Hill · USWest Health · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
EPIDEMIOLOGY AND BIOSTATISTICS OF AGINGT32AG000247 · NIA · JOHNS HOPKINS UNIVERSITY · PI Karen J. Bandeen-Roche · 1996 to 2026
$13.2M
Growing the Geriatric Emergency care Applied Research (GEAR 1.1) network: Expanding and sustaining an emergency care aging study infrastructure.R33AG058926 · NIA · YALE UNIVERSITY · PI Ula Y Hwang, Daniella Meeker · 2020 to 2026
$4.6M
Mentoring and Research in Patient-Oriented Geriatric Emergency CareK24AG054560 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI SHAH, MANISH N · 2017 to 2021
$955k
Building the Geriatric Emergency care Applied Research (GEAR) networkR21AG058926 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HWANG, ULA Y · 2018 to 2019
$463k
NCATS NIH HHS UL1 TR001863NIA NIH HHS K24 AG054560NIA NIH HHS K24AG054560-01NIA NIH HHS R21 AG058926NIA NIH HHS R21AG058926NIA NIH HHS R33 AG058926NIA NIH HHS T32 AG000247
6 · The paper itself

Abstract

backgroundOlder adult delirium is often unrecognized in the emergency department (ED), yet the most compelling research questions to overcome knowledge-to-practice deficits remain undefined. The Geriatric Emergency care Applied Research (GEAR) Network was organized to identify and prioritize delirium clinical questions.

methodsGEAR identified and engaged 49 transdisciplinary stakeholders including emergency physicians, geriatricians, nurses, social workers, pharmacists, and patient advocates. Adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews, clinical questions were derived, medical librarian electronic searches were conducted, and applicable research evidence was synthesized for ED delirium detection, prevention, and management. The scoping review served as the foundation for a consensus conference to identify the highest priority research foci.

resultsIn the scoping review, 27 delirium detection "instruments" were described in 48 ED studies and used variable criterion standards with the result of delirium prevalence ranging from 6% to 38%. Clinician gestalt was the most common "instrument" evaluated with sensitivity ranging from 0% to 81% and specificity from 65% to 100%. For delirium management, 15 relevant studies were identified, including one randomized controlled trial. Some intervention studies targeted clinicians via education and others used clinical pathways. Three medications were evaluated to reduce or prevent ED delirium. No intervention consistently prevented or treated delirium. After reviewing the scoping review results, the GEAR stakeholders identified ED delirium prevention interventions not reliant on additional nurse or physician effort as the highest priority research.

conclusionsTransdisciplinary stakeholders prioritize ED delirium prevention studies that are not reliant on health care worker tasks instead of alternative research directions such as defining etiologic delirium phenotypes to target prevention or intervention strategies.

Indexed as

DeliriumEmergency Medical ServicesEmergency MedicineAgedEmergency Service, HospitalGeriatric AssessmentHumans

Identifiers

PMID33135274
PMCPMC7971946
OpenAlexW3095508914

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.