Evidence map›Paper›PMID 33135100›Full record

ArticleAbdominal radiology (New York)2021

Quantitative assessment of disease severity of primary sclerosing cholangitis with T1 mapping and extracellular volume imaging.

Sehnaz Evrimler, Jordan K Swensson, Vijay S Are, Temel Tirkes, Raj Vuppalanchi, Fatih Akisik

Abstract read
PubMed Publisher
In one paragraph

Article in Abdominal radiology (New York), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Abdominal simultaneous 3D water TMagnetic resonance in medicine · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sehnaz EvrimlerDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N University Blvd Room 0663, Indianapolis, IN, 46202, USA.
Jordan K SwenssonDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N University Blvd Room 0663, Indianapolis, IN, 46202, USA.
Vijay S AreDepartment of Gastroenterology and Hepatology, Indiana University School of Medicine, 702 Rotary Circle Room 225, Indianapolis, IN, 46202, USA.
Temel TirkesDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N University Blvd Room 0663, Indianapolis, IN, 46202, USA.
Raj VuppalanchiDepartment of Gastroenterology and Hepatology, Indiana University School of Medicine, 550 N University Blvd Room 1710, Indianapolis, IN, 46202, USA.
Fatih AkisikDepartment of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N University Blvd Room 0663, Indianapolis, IN, 46202, USA. makisik@iupui.edu.ORCID http://orcid.org/0000-0003-3176-0718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAssess the relationship between liver T1 relaxation time and extracellular volume (ECV) fraction and the disease severity of primary sclerosing cholangitis (PSC).

methodsThis retrospective study included 93 patients with PSC and 66 healthy patients in the control group. T1 relaxation times were measured in the right and left lobe, as well as in the area of stricture. T1

resultsMean liver T1 (774 ± 111 ms, p < 0.001) and liver ECV (0.40 ± 0.14, p < 0.05) were significantly higher with both large-duct and small-duct-type PSC which may lack classic imaging findings on MRCP compared to the control group (p < 0.001). T1

conclusionT1 relaxation time and ECV fraction can be used for quantitative assessment of disease severity in patients with PSC.

Indexed as

Cholangitis, SclerosingElasticity Imaging TechniquesHumansLiverRetrospective StudiesSeverity of Illness IndexExtracellular volumeLiverMagnetic resonance imagingPrimary sclerosing cholangitisT1 relaxometry

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.