Evidence map›Paper›PMID 33135093›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging.

Roberto Sciagrà, Mark Lubberink, Fabien Hyafil, Antti Saraste, Riemer H J A Slart, Denis Agostini, Carmela Nappi, Panagiotis Georgoulias, Jan Bucerius, Christoph Rischpler and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04941248 (The Application of Total-body 13N-NH3 PET/CT to Study the Blood Perfusion System in Severe AS Patients Before and After TAVR Surgery in the Whole Body), which is not on this map. Cited by 77 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04941248 completednot on this map

The Application of Total-body 13N-NH3 PET/CT to Study the Blood Perfusion System in Severe AS Patients Before and After TAVR Surgery in the Whole Body

TypeobservationalSponsorRenJi HospitalRan2021 to 2026Enrolled34ConditionsCardiac OutputArmstotal-body PET/CT(uEXPLORER , United Imaging Healthcare, China)
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  5. Article
  6. Cardiovascular imaging with total-body PET.The British journal of radiology · 2026
    Review
  7. Article
  8. Article
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  12. Article
  13. Enhanced accuracy of cardiacEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
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  16. Article
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  19. Article
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Roberto SciagràNuclear Medicine Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Largo Brambilla 3, 50134, Florence, Italy. roberto.sciagra@unifi.it.ORCID http://orcid.org/0000-0003-0694-2552
Mark LubberinkRadiology & Molecular Imaging, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Fabien HyafilDepartment of Nuclear Medicine, DMU IMAGINA, APHP, Hôpital Européen Georges-Pompidou, University of Paris, Paris, France.
Antti SarasteTurku PET Centre, Turku University Hospital, University of Turku, Turku, Finland.
Riemer H J A SlartDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands.
Denis AgostiniDepartment of Nuclear Medicine, CHU Cote de Nacre, Normandy University, EA 4650, Caen, France.
Carmela NappiDepartment of Advanced Biomedical Sciences, University Federico II, Naples, Italy.
Panagiotis GeorgouliasDepartment of Nuclear Medicine, Faculty of Medicine, University of Thessaly, University Hospital of Larissa, Larissa, Greece.
Jan BuceriusDepartment of Nuclear Medicine, University Medicine Göttingen, Georg-August University Göttingen, Göttingen, Germany.
Christoph RischplerDepartment of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Hein J VerberneDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands.
Cardiovascular Committee of the European Association of Nuclear Medicine (EANM)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of cardiac PET, and in particular of quantitative myocardial perfusion PET, has been growing during the last years, because scanners are becoming widely available and because several studies have convincingly demonstrated the advantages of this imaging approach. Therefore, there is a need of determining the procedural modalities for performing high-quality studies and obtaining from this demanding technique the most in terms of both measurement reliability and clinical data. Although the field is rapidly evolving, with progresses in hardware and software, and the near perspective of new tracers, the EANM Cardiovascular Committee found it reasonable and useful to expose in an updated text the state of the art of quantitative myocardial perfusion PET, in order to establish an effective use of this modality and to help implementing it on a wider basis. Together with the many steps necessary for the correct execution of quantitative measurements, the importance of a multiparametric approach and of a comprehensive and clinically useful report have been stressed.

Indexed as

Cardiovascular SystemMyocardial Perfusion ImagingHumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadioisotopesReproducibility of ResultsRadioisotopesMyocardial blood flowMyocardial flow reservePETQuantitative imaging

Identifiers

PMID33135093
PMCPMC7603916

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.