ArticleIEEE transactions on radiation and plasma medical sciences2020
Total Body PET: Why, How, What for?
Article in IEEE transactions on radiation and plasma medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 133 citations in OpenAlex.
- Deep unrolled regularization for limited-angle dual-panel positron emission mammography.Physical and engineering sciences in medicine · 2026Article
- Realization of long axial field-of-view PET technology in the clinic and research environment.The British journal of radiology · 2026Review
- Superiority of long axial field-of-viewEuropean journal of nuclear medicine and molecular imaging · 2026Article
- The clinical utility of total-body [European journal of nuclear medicine and molecular imaging · 2026Article
- A Virtual Clinical Trial to Detect Changes in Tumor Uptake with PET using Lesion Embedding.IEEE transactions on radiation and plasma medical sciences · 2026Article
- Performance evaluation of the nanoScanEJNMMI physics · 2025Article
- Long Axial Field-of-view PET: A New Era of Quantitative PET Imaging for Theranostic Applications in Clinic.PET clinics · 2025Review
- Randoms Estimation for Long Axial Field-of-View PET.IEEE transactions on radiation and plasma medical sciences · 2025Article
- Impact of deep learning denoising on kinetic modelling for low-dose dynamic PET: application to single- and dual-tracer imaging protocols.European journal of nuclear medicine and molecular imaging · 2025Article
- Evaluation of deep learning-based scatter correction on a long-axial field-of-view PET scanner.European journal of nuclear medicine and molecular imaging · 2025Article
- Performance evaluation of a medium axial field-of-view sparse PET system based on flat panels of monolithic LYSO detectors: a simulation study.EJNMMI physics · 2025Article
- Nonmaximal entanglement of photons from positron-electron annihilation demonstrated using a plastic PET scanner.Science advances · 2025Article
- Realistic total-body J-PET geometry optimization: Monte Carlo study.Medical physics · 2025Article
- Multi-angle acquisition and 3D composite reconstruction for organ-targeted PET using planar detectors.Medical physics · 2025Article
- Assessment of fully quantitative and simplified methods for analysis of [European journal of nuclear medicine and molecular imaging · 2025Article
- Total-Body PET System Designs with Axial and Transverse Gaps: A Study of Lesion Quantification and Detectability.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Article
- Total Body PET/CT: Future Aspects.Seminars in nuclear medicine · 2025Review
- PET in the characterization of immune diseases and development of therapeutics.Oxford open immunology · 2025Review
- Optimization and impact of sensitivity mode on abbreviated scan protocols with population-based input function for parametric imaging of [European journal of nuclear medicine and molecular imaging · 2024Article
- Performance and application of the total-body PET/CT scanner: a literature review.EJNMMI research · 2024Review
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
PET instruments are now available with a long axial field-of-view (LAFOV) to enable imaging the total-body, or at least head and torso, simultaneously and without bed translation. This has two major benefits, a dramatic increase in system sensitivity and the ability to measure kinetics with wider axial coverage so as to include multiple organs. This manuscript presents a review of the technology leading up to the introduction of these new instruments, and explains the benefits of a LAFOV PET-CT instrument. To date there are two platforms developed for TB-PET, an outcome of the EXPLORER Consortium of the University of California at Davis (UC Davis) and the University of Pennsylvania (Penn). The uEXPLORER at UC Davis has an AFOV of 194 cm and was developed by United Imaging Healthcare. The PennPET EXPLORER was developed at Penn and is based on the digital detector from Philips Healthcare. This multi-ring system is scalable and has been tested with 3 rings but is now being expanded to 6 rings for 140 cm. Initial human studies with both EXPLORER systems have demonstrated the successful implementation and benefits of LAFOV scanners for both clinical and research applications. Examples of such studies are described in this manuscript.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.