Evidence map›Paper›PMID 33134599›Full record

ArticleJournal of the anus, rectum and colon2020

Clinical Results of One-stage Restorative Proctocolectomy with J-pouch Anal Anastomosis in 300 Ulcerative Colitis Patients.

Ryuichi Kuwahara, Hiroki Ikeuchi, Toshihiro Bando, Hirohumi Sasaki, Yoshiko Goto, Yuki Horio, Tomohiro Minagawa, Motoi Uchino

Abstract read
In one paragraph

Article in Journal of the anus, rectum and colon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ryuichi KuwaharaDepartment of Gastroenterology, Division of Inflammatory Bowel Disease, Hyogo College of Medicine, Nisinomiya, Japan.
Hiroki IkeuchiDepartment of Gastroenterology, Division of Inflammatory Bowel Disease, Hyogo College of Medicine, Nisinomiya, Japan.
Toshihiro BandoDepartment of Gastroenterology, Division of Inflammatory Bowel Disease, Hyogo College of Medicine, Nisinomiya, Japan.
Hirohumi SasakiDepartment of Gastroenterology, Division of Inflammatory Bowel Disease, Hyogo College of Medicine, Nisinomiya, Japan.
Yoshiko GotoDepartment of Gastroenterology, Division of Inflammatory Bowel Disease, Hyogo College of Medicine, Nisinomiya, Japan.
Yuki HorioDepartment of Gastroenterology, Division of Inflammatory Bowel Disease, Hyogo College of Medicine, Nisinomiya, Japan.
Tomohiro MinagawaDepartment of Gastroenterology, Division of Inflammatory Bowel Disease, Hyogo College of Medicine, Nisinomiya, Japan.
Motoi UchinoDepartment of Gastroenterology, Division of Inflammatory Bowel Disease, Hyogo College of Medicine, Nisinomiya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesRestorative proctocolectomy and ileal pouch anal anastomosis (IPAA), with diverting ileostomy, are established ulcerative colitis (UC) treatments. The routine use of diverting ileostomy is controversial because of the risk of stoma closure and stoma related complications. In our institution, proctocolectomy and IPAA, with mucosectomy and handsewn anastomosis without diversion (one-stage IPAA), were performed for select patients with UC. The present study aimed to evaluate the clinical and functional outcomes of patients undergoing one-stage IPAA.

methodsBetween April 1999 and July 2017, 300 patients underwent one-stage IPAA in our institution. The clinical notes and prognosis were reviewed retrospectively.

resultsPostoperative complications (Clavien-Dindo classification grade ≥III) occurred in 18 patients (6.0%). The most common complication was anastomotic leakage (n = 9, 3%). There were 15 patients (5.0%) who required a defunctioning ileostomy. However, 13 patients successfully underwent ileostomy closure and achieved acceptable pouch function. Finally, two patients (0.6%) required pouch excision in this series. The cumulative pouch functional rate was 99.6% / 5 years and 99.2% / 10 years.

conclusionsOne-stage IPAA is a good strategy for carefully selected patients with UC.

Indexed as

restorative proctocolectomyulcerative colitiswithout diverting ileostomy

Identifiers

PMID33134599
PMCPMC7595683

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.