ArticlePhysics and imaging in radiation oncology2020
Clinical experience and workflow challenges with magnetic resonance-only radiation therapy simulation and planning for prostate cancer.
Article in Physics and imaging in radiation oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Focal radiotherapy boost to MR-visible tumor for prostate cancer: a systematic review.World journal of urology · 2024Pooled it
- Evaluation of AI-based segmentation and synthetic CT generation for MRI-only prostate radiotherapy planning.Journal of applied clinical medical physics · 2026Article
- Evaluation of Magnetic Resonance Imaging-Derived Synthetic Computed Tomography in Prostate Cancer Carbon Ion Radiotherapy: Impact of Fixation Shell.International journal of particle therapy · 2026Article
- Dose differences between patients treated with MR-only, CT-only, or MR-CT fusion radiotherapy for prostate cancer.The British journal of radiology · 2025Article
- PrecisionPro Fusion: Clinical validation of an automated, rigid, Prostate-Specific MRI-CT Fusion system for prostate radiotherapy planning.Technical innovations & patient support in radiation oncology · 2025Article
- Steps towards overcoming challenges in clinical practice at 1.5T MR-Linac for lung cancer adaptive radiotherapy.BMC cancer · 2025Article
- The Use of Magnetic Resonance Imaging in Radiation Therapy Treatment Simulation and Planning.Journal of magnetic resonance imaging : JMRI · 2024Review
- Feasibility of quantitative relaxometry for prostate target localization and response assessment in magnetic resonance-guided online adaptive stereotactic body radiotherapy.Physics and imaging in radiation oncology · 2024Article
- Advancing the Collaboration Between Imaging and Radiation Oncology.Seminars in radiation oncology · 2024Review
- Automatic AI-based contouring of prostate MRI for online adaptive radiotherapy.Zeitschrift fur medizinische Physik · 2024Article
- Evolving concepts in margin strategies and adaptive radiotherapy for glioblastoma: A new future is on the horizon.Neuro-oncology · 2024Review
- Potential dosimetric error in the adaptive workflow of a 1.5 T MR-Linac from patient movement relative to immobilisation systems.Physical and engineering sciences in medicine · 2024Article
- Patient-specific quality assurance strategies for synthetic computed tomography in magnetic resonance-only radiotherapy of the abdomen.Physics and imaging in radiation oncology · 2023Article
- MRI-only radiotherapy from an economic perspective: Can new techniques in prostate cancer treatment be cost saving?Clinical and translational radiation oncology · 2023Article
- Stereotactic body radiation therapy for hepatocellular carcinoma: From infancy to ongoing maturity.JHEP reports : innovation in hepatology · 2022Review
- An evaluation of quality assurance guidelines comparing the American College of Radiology and American Association of Physicists in Medicine task group 284 for magnetic resonance simulation.Journal of applied clinical medical physics · 2022Article
- The Promise of Magnetic Resonance Imaging in Radiation Oncology Practice in the Management of Brain, Prostate, and GI Malignancies.JCO global oncology · 2022Review
- Improving the clinical workflow of a MR-Linac by dosimetric evaluation of synthetic CT.Frontiers in oncology · 2022Article
- Deep learning-based classification and structure name standardization for organ at risk and target delineations in prostate cancer radiotherapy.Journal of applied clinical medical physics · 2021Article
- [Primary treatment of prostate cancer using 1.5 T MR-linear accelerator].Der Radiologe · 2021Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
background and purposeMagnetic Resonance (MR)-only planning has been implemented clinically for radiotherapy of prostate cancer. However, fewer studies exist regarding the overall success rate of MR-only workflows. We report on successes and challenges of implementing MR-only workflows for prostate. MATERIALS AND
methodsA total of 585 patients with prostate cancer underwent an MR-only simulation and planning between 06/2016-06/2018. MR simulation included images for contouring, synthetic-CT generation and fiducial identification. Workflow interruptions occurred that required a backup CT, a re-simulation or an update to our current quality assurance (QA) process. The challenges were prospectively evaluated and classified into syn-CT generation, motion/artifacts in the MRs, fiducial QA and bowel preparation guidelines.
resultsMR-only simulation was successful in 544 (93.2 %) patients. . In seventeen patients (2.9%), reconstruction of synthetic-CT failed due to patient size, femur angulation, or failure to determine the body contour. Twenty-four patients (4.1%) underwent a repeat/backup CT scan because of artifacts on the MR such as image blur due to patient motion or biopsy/surgical artifacts that hampered identification of the implanted fiducial markers. In patients requiring large coverage due to nodal involvement, inhomogeneity artifacts were resolved by using a two-stack acquisition and adaptive inhomogeneity correction. Bowel preparation guidelines were modified to address frequent rectum/gas issues due to longer MR scan time.
conclusionsMR-only simulation has been successfully implemented for a majority of patients in the clinic. However, MR-CT or CT-only pathway may still be needed for patients where MR-only solution fails or patients with MR contraindications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.