Evidence map›Paper›PMID 33134532›Full record

ArticleLaryngoscope investigative otolaryngology2020

The Functional & Quality of Life Outcomes of Total Glossectomy with Laryngeal Preservation.

Justin M Pyne, Peter T Dziegielewski, Gabriela Constantinescu, Agnieszka Dzioba, Daniel A O'Connell, David W J Côté, Khalid Ansari, Jeffrey Harris, Dustin Conrad, Fawaz M Makki and 3 more

Open access · goldAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Five-year long-term functional and quality of life outcomes in total glossectomy survivors.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  5. Article
  6. Advanced mandibular reconstruction with fibular free flap and alloplastic TMJ prosthesis with digital planning.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 3 countries.

Justin M PyneDepartment of Surgery, Division of Otolaryngology - Head and Neck Surgery University of Alberta Edmonton Alberta Canada.
Peter T DziegielewskiDepartment of Otolaryngology University of Florida Gainesville Florida USA.
Gabriela ConstantinescuInstitute for Reconstructive Sciences in Medicine Caritas Health Group Edmonton Alberta Canada.ORCID https://orcid.org/0000-0001-7709-6547
Agnieszka DziobaDepartment of Surgery, Division of Otolaryngology - Head and Neck Surgery University of Alberta Edmonton Alberta Canada.
Daniel A O'ConnellDepartment of Surgery, Division of Otolaryngology - Head and Neck Surgery University of Alberta Edmonton Alberta Canada.
David W J CôtéDepartment of Surgery, Division of Otolaryngology - Head and Neck Surgery University of Alberta Edmonton Alberta Canada.
Khalid AnsariDepartment of Surgery, Division of Otolaryngology - Head and Neck Surgery University of Alberta Edmonton Alberta Canada.
Jeffrey HarrisDepartment of Surgery, Division of Otolaryngology - Head and Neck Surgery University of Alberta Edmonton Alberta Canada.
Dustin ConradDepartment of Surgery, Division of Otolaryngology - Head and Neck Surgery University of Alberta Edmonton Alberta Canada.
Fawaz M MakkiDepartment of Surgery, Division of Otolaryngology - Head and Neck Surgery University of Alberta Edmonton Alberta Canada.
Matthew HearnDepartment of Surgery, Division of Otolaryngology - Head and Neck Surgery University of Alberta Edmonton Alberta Canada.
Vincent L BironDepartment of Surgery, Division of Otolaryngology - Head and Neck Surgery University of Alberta Edmonton Alberta Canada.ORCID https://orcid.org/0000-0002-7661-5277
Hadi SeikalyDepartment of Surgery, Division of Otolaryngology - Head and Neck Surgery University of Alberta Edmonton Alberta Canada.ORCID https://orcid.org/0000-0002-8939-1364
University of Alberta · CAUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe tongue is an essential organ for human interaction, communication and survival. To date, there is a paucity of objective functional, patient reported, or quality of life outcomes of patients undergoing a total glossectomy with preservation of the larynx (TGLP).

objectiveTo examine prospectively collected objective, self-reported functional and quality of life (QOL) data in patients undergoing TGLP and free flap reconstruction.

methodsSixteen TGLP patients were identified in the prospective head and neck cancer and functional outcomes database between January of 2009 and December 2017. Data collection included patient age, sex, performance status, TNM staging, diagnosis and adjuvant treatment. Swallowing and speech functions were measured and prospectively recorded pre- and postoperatively. Patient reported outcomes were measured with the Speech Handicap Index (SHI) and the M.D. Anderson Dysphagia Inventory (MDADI).

resultsAll patients had a significant reduction in their objective swallowing (

conclusionTotal glossectomy with laryngeal sparing and free flap reconstruction results in significant reduction in objective functional measurements, but patients report stable functional and quality of life outcomes after treatment.

Indexed as

anterolateral thigh free‐flapfree‐flapfunctional outcomeslarynx preservationoral cancerquality of lifetotal glossectomy

Identifiers

PMID33134532
PMCPMC7585251
OpenAlexW3049259193

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.