Evidence map›Paper›PMID 33134482›Full record

ArticleTransplantation direct2020

Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation.

Adrian M Whelan, Kirsten L Johansen, Charles E McCulloch, Dieter Adelmann, Claus U Niemann, Garrett R Roll, Salpi Siyahian, Barbara Grimes, Elaine Ku

Abstract read
In one paragraph

Article in Transplantation direct, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Increased volume of organ offers and decreased efficiency of kidney placement under circle-based kidney allocation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adrian M WhelanDivision of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, CA.
Kirsten L JohansenDivision of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, CA.
Charles E McCullochDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA.
Dieter AdelmannDepartment of Anesthesia and Critical Care, University of California, San Francisco, San Francisco, CA.
Claus U NiemannDepartment of Anesthesia and Critical Care, University of California, San Francisco, San Francisco, CA.
Garrett R RollDivision of Transplant Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA.
Salpi SiyahianDivision of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, CA.
Barbara GrimesDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA.
Elaine KuDivision of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, CA.

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
Racial disparities in access to kidney transplantationR01DK115629 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI R. Adams Dudley, KIRSTEN L. JOHANSEN · 2018 to 2026
$4.5M
Prevalence and Impact of Frailty among Dialysis PatientsK24DK085153 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHANSEN, KIRSTEN L. · 2010 to 2021
$1.5M
Blood pressure trends, outcomes, and interventions in adolescents and young adults at increased cardiovascular riskK23HL131023 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KU, ELAINE · 2016 to 2020
$991k
NCATS NIH HHS UL1 TR001872NHLBI NIH HHS K23 HL131023NIDDK NIH HHS K24 DK085153NIDDK NIH HHS R01 DK115629
6 · The paper itself

Abstract

Rates of kidney transplantation vary substantially across dialysis facilities in the United States. Whether distance between the dialysis facility and transplant center associates with variations in transplantation rates has not been examined.

methodsWe performed a retrospective study of adults treated with dialysis between 2005 and 2015, according to the US Renal Data System. We examined the association between distance from dialysis facility to transplant center and time to kidney transplantation (primary outcome) and waitlist registration (secondary outcome) using Fine-Gray models. We also performed sensitivity analyses using the distance from each patient's dialysis facility to the nearest transplant center as the predictor so that patients who were never registered on the waitlist (and therefore would not have a transplant center) could be included.

resultsIn total, 178 885 waitlisted patients were included for our primary analysis. As distance between dialysis facility and transplant center increased, lower hazard of transplantation (subhazard ratio [HR], 0.92; 95% confidence interval [CI], 0.91-0.94, if distance was 10 to <50 miles; sub-HR, 0.90; 95% CI, 0.88-0.92, if distance ≥50 miles compared with <10 miles) was noted. We also found a weak association between longer distance and hazard of waitlist registration (sub-HR, 0.96; 95% CI, 0.94-0.97, if distance was ≥50 miles versus <10 miles). Findings were similar in sensitivity analyses using distance between dialysis facility and the nearest transplant center (N = 1 149 721).

conclusionsPatients receiving dialysis in facilities located further away from transplant centers have lower hazard of kidney transplantation. Developing strategies to address barriers to transplantation in patients receiving dialysis at facilities located far away from a transplant center may help improve disparities in transplantation rates.

Identifiers

PMID33134482
PMCPMC7591118

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.