ArticleSSM - population health2020
Increases in BMI and chronic pain for US adults in midlife, 1992 to 2016.
Article in SSM - population health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 47 citations in OpenAlex.
- Characterization of Patient-Reported Loin Pain in IgAN.Kidney international reports · 2026Article
- Effects of preoperative anti-PD-1 therapy on intraoperative and postoperative analgesia in patients undergoing radical esophagectomy: a retrospective cohort study.Scientific reports · 2026Article
- Pain during midlife: a cross-national analysis of cohort differences in reports of pain in the United States, Europe, South Korea, and Mexico.American journal of epidemiology · 2026Article
- Educational Disparities in Disability in Mid- to Late-Life: How Much is Attributable to Pain?Journal of aging and health · 2026Article
- Age-specific trends in limitations of daily activities in American adults aged 50-84 by race and ethnicity, 2000-2018.PloS one · 2026Article
- Chronic pain and mortality risk among middle-age and older Japanese: the Shika town cohort study.Pain reports · 2025Article
- Risk factors with nomogram construction for moderate to severe pain after endoscopic full-thickness resection.World journal of gastroenterology · 2025Article
- Chronic pain prevalence and trends in urban, suburban, and rural areas among American adults aged 55+, 1998-2022.Social science & medicine (1982) · 2025Article
- Social factors contributing to the development of chronic low back pain: a scoping review.BMC musculoskeletal disorders · 2025Article
- Bayesian-weighted Mendelian randomization reveals sleep apnea syndrome mediates the BMI-chronic pain link.Journal of thoracic disease · 2025Article
- Research trends and hot spots in obesity-induced pain: A bibliometric analysis of the last 20 years.IBRO neuroscience reports · 2025Review
- Obesity and Systemic Inflammation Disrupt the Compensatory Role of Physical Activity in Chronic Pain Conditions.Biomedicines · 2025Article
- Article
- Pain Management Services Can Be a Cost-Effective Option over Surgery for the Treatment of Chronic Pain.Current pain and headache reports · 2025Review
- Middle East Pain Registry (MEPAIN): Feasibility Study of Chronic Pain Registry and Pilot Phase Results : Middle East Pain Registry (MEPAIN).Galen medical journal · 2025Article
- An exploration of the increasing prevalence of chronic pain among Canadian veterans: Life After Service Studies 2016 and 2019.Canadian journal of pain = Revue canadienne de la douleur · 2025Article
- Multisite Chronic Pain and the Risk of Breast Cancer and Its Subtypes: A Mendelian Randomization Study.Journal of pain research · 2025Article
- Are We Adding Pain-Free Years to Life? A Test of Compression Versus Expansion of Morbidity.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Educational attainment, family background and the emergence of pain gradients in adulthood.Social science & medicine (1982) · 2024Article
- Perceived Neighborhood Characteristics and Later-Life Pain Outcomes: Evidence From the Health and Retirement Study.Journal of aging and health · 2024Article
Corrections and comments
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Authors and funding
9 authors at 7 institutions in 2 countries.
Funding
Abstract
Recent unprecedented increases in mortality and morbidity during midlife are often ascribed to rising despair in the US population. An alternative and less often examined explanation is that these trends reflect, at least in part, the lagged effects of the obesity epidemic. Adults in midlife today are more likely to live with obesity and have a greater cumulative exposure to excess adiposity during their lifetime than any previous generation. Prior work has demonstrated a link between obesity and mortality risk at midlife, but the mechanisms remain unclear. Pain may represent one important pathway linking obesity to mortality trends. Pain is a debilitating condition that has increased significantly over recent decades and is associated with both morbidity and mortality, including suicide and opioid-related mortality. Evidence suggests obesity and pain may be linked, but there is little evidence of an association at the population level. In this paper, we examine to what extent increases in overweight and obesity explain the rising trends in chronic pain observed among middle-aged adults in the US from 1992 to 2016. We assess trends in both mild/moderate nonlimiting pain and severe and/or limiting pain. In doing so, we draw attention to one mechanism through which overweight/obesity may have contributed to recent population health trends. Our analysis found that increases in BMI from 1992 to 2016 may account for up to 20% of the upward trend in mild/moderate nonlimiting pain and 32% of the trend in severe and/or limiting pain for women, and 10% and 19% of the trends respectively for men.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.