Evidence map›Paper›PMID 33134419›Full record

ArticleOpen forum infectious diseases2020

Case Report: Overwhelming

Yijia Li, Susan Stanley, Julian A Villalba, Sandra Nelson, Jeffrey Gelfand

Abstract readCase Reports
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Human babesiosis: The past, present and future.Expert reviews in molecular medicine · 2025
    Review
  3. Review
  4. Treatment of Human Babesiosis: Then and Now.Pathogens (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yijia LiInfectious Diseases Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-5300-0571
Susan StanleyInfectious Diseases Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.
Julian A VillalbaDepartment of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Sandra NelsonInfectious Diseases Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jeffrey GelfandInfectious Diseases Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Babesiosis with high-grade parasitemia is life-threatening, especially in asplenic hosts. We report an asplenic patient with parasitemia >50% who was successfully treated with prompt red blood cell apheresis and triple therapy with clindamycin + azithromycin + atovaquone. This regimen may be an alternative to poorly tolerated clindamycin + quinine in severe cases.

Indexed as

aphresisatovaquoneazithromycinbabesiaquinine

Identifiers

PMID33134419
PMCPMC7585322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.