Evidence map›Paper›PMID 33134326›Full record

ArticleFrontiers in cardiovascular medicine2020

Noncanonical WNT Activation in Human Right Ventricular Heart Failure.

Jonathan J Edwards, Jeffrey Brandimarto, Dong-Qing Hu, Sunhye Jeong, Nora Yucel, Li Li, Kenneth C Bedi, Shogo Wada, Danielle Murashige, Hyun Tae V Hwang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Wnt5a-mediated Adipo-Cardiac Interorgan Communication in HFpEF.bioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Wnt signaling in cardiac development and heart diseases.In vitro cellular & developmental biology. Animal · 2024
    Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Jonathan J EdwardsDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Jeffrey BrandimartoCardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Dong-Qing HuDivision of Cardiology, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA, United States.
Sunhye JeongCardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Nora YucelCardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Li LiCardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Kenneth C BediCardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Shogo WadaCardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Danielle MurashigeCardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Hyun Tae V HwangDivision of Cardiology, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA, United States.
Mingming ZhaoDivision of Cardiology, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA, United States.
Kenneth B MarguliesCardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Daniel BernsteinDivision of Cardiology, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA, United States.
Sushma ReddyDivision of Cardiology, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA, United States.
Zoltan AranyCardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
University of Pennsylvania · USStanford University · USLucile Packard Children's Hospital · US

Funding

Training in Molecular Therapeutics for Pediatric CardiologyT32HL007915 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI Robert J Levy, JOSEPH W ROSSANO · 1999 to 2026
$13.4M
Integrative genomics of human heart failureR01HL105993 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI ASHLEY, EUAN A, CAPPOLA, THOMAS P. · 2011 to 2014
$8.9M
Branched chain amino acids in heart failureR01HL152446 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Zoltan P Arany · 2020 to 2026
$3.7M
Non-cardiomyocyte miR-34a Mediates Susceptibility to Right Heart FailureK08HL127277 · NHLBI · STANFORD UNIVERSITY · PI REDDY, SUSHMA · 2015 to 2019
$804k
Branched Chain Amino Acids and Heart FailureF30HL142186 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MURASHIGE, DANIELLE · 2019 to 2022
$116k
NHLBI NIH HHS F30 HL142186NHLBI NIH HHS K08 HL127277NHLBI NIH HHS R01 HL105993NHLBI NIH HHS R01 HL152446NHLBI NIH HHS T32 HL007915
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

calpainheart failureremodelingright ventricle (RV)right ventricular (RV) failureRor2Wnt

Identifiers

PMID33134326
PMCPMC7575695
OpenAlexW3091886533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.