Evidence map›Paper›PMID 33134263›Full record

ArticleFrontiers in chemistry2020

Development of an Approach of High Sensitive Chemiluminescent Assay for Cystatin C Using a Nanoparticle Carrier.

Yuanjie Sun, Liang Tao, Ying Ma, Shuya Yang, Xiyang Zhang, Boquan Jin, Zhujun Zhang, Kun Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yuanjie SunDepartment of Immunology, The Fourth Military Medical University, Shaanxi, China.
Liang TaoDepartment of Immunology, The Fourth Military Medical University, Shaanxi, China.
Ying MaDepartment of Immunology, The Fourth Military Medical University, Shaanxi, China.
Shuya YangDepartment of Immunology, The Fourth Military Medical University, Shaanxi, China.
Xiyang ZhangDepartment of Immunology, The Fourth Military Medical University, Shaanxi, China.
Boquan JinDepartment of Immunology, The Fourth Military Medical University, Shaanxi, China.
Zhujun ZhangKey Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Shaanxi, China.
Kun YangDepartment of Immunology, The Fourth Military Medical University, Shaanxi, China.
Air Force Medical University · CNShaanxi Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystatin C is an important cysteine protease inhibitor in the human body and is proposed as a new indicator of glomerular filtration rate for the detection of kidney damage. In this article, we report an ultra-sensitive, simple, and rapid chemiluminescence immunoassay method for cystatin C detection using functionalized mesoporous silica nanoparticles. After a three step hydrolysis, the amino-functionalized MSN encapsulating dye resulted in a hydrophobic environment for fixing the dye and amino groups for biological modification. The NaIO

Indexed as

cystatin Cenhanced chemiluminescencefluoresceinmesoporous silica nanoparticleNaIO4 immobilization methodRhodamine 6G

Identifiers

PMID33134263
PMCPMC7505105
OpenAlexW3083864331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.