ArticleFrontiers in public health2020
Health Disparities in COVID-19: Addressing the Role of Social Determinants of Health in Immune System Dysfunction to Turn the Tide.
Article in Frontiers in public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Integrating mathematical modelling and artificial intelligence to combat emerging viral syndemics: A systematic review.New microbes and new infections · 2026Review
- Macrovascular Function in People with HIV After Recent SARS-CoV-2 Infection.Journal of vascular diseases · 2025Article
- Longer-Term Mental Health Consequences of COVID-19 Infection: Moderation by Race and Socioeconomic Status.International journal of behavioral medicine · 2025Article
- Teaching at the intersection of science and society: An activity on healthcare disparities.Biology methods & protocols · 2024Article
- Associations between neighborhood socioeconomic deprivation, IFNγ, and high-density lipoprotein particle size: Data from the Washington, D.C. cardiovascular health and needs assessment.Psychoneuroendocrinology · 2023Observational
- [Social, demographic and morbimortality characteristics of the cases treated for COVID-19 at the Ignacio Chávez National Institute of Cardiology. A descriptive cross-sectional study].Archivos de cardiologia de Mexico · 2023Article
- By what molecular mechanisms do social determinants impact cardiometabolic risk?Clinical science (London, England : 1979) · 2023Review
- Can digital health researchers make a difference during the pandemic? Results of the single-arm, chatbot-led Elena+: Care for COVID-19 interventional study.Frontiers in public health · 2023Article
- Social determinants of health associated with COVID-19 severity during pregnancy: a multinational cohort study (in the International Registry of Coronavirus Exposure in Pregnancy).BMC public health · 2022Observational
- Meeting the Challenges of Myocarditis: New Opportunities for Prevention, Detection, and Intervention-A Report from the 2021 National Heart, Lung, and Blood Institute Workshop.Journal of clinical medicine · 2022Article
- Baseline risk characterization of early versus later adopters of long-acting paliperidone palmitate formulations.Neuropsychopharmacology reports · 2022Article
- COVID-19, Race/Ethnicity, and Age: the Role of Telemedicine to Close the Gaps on Health Disparities.Journal of economics, race, and policy · 2022Article
- Spatial Clustering of County-Level COVID-19 Rates in the U.S.International journal of environmental research and public health · 2021Article
- Dynamics of Covid-19 mortality and social determinants of health: a spatiotemporal analysis of exceedance probabilities.Annals of epidemiology · 2021Article
- Association of Socioeconomic Characteristics With Disparities in COVID-19 Outcomes in Japan.JAMA network open · 2021Article
- Article
- How patients with COVID-19 managed the disease at home during the first wave in Spain: a cross-sectional study.BMJ open · 2021Article
- Socio-economic impact on epilepsy outside of the nation-wide COVID-19 pandemic area.Epilepsy & behavior : E&B · 2021Article
- Clinical and hospitalisation predictors of COVID-19 in the first month of the pandemic, Portugal.PloS one · 2021Article
- Elena+ Care for COVID-19, a Pandemic Lifestyle Care Intervention: Intervention Design and Study Protocol.Frontiers in public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
It is evident that health disparities exist during the COVID-19 pandemic, a pandemic caused by the novel coronavirus SARS-CoV-2. Underlying reasons for COVID-19 health disparities are multi-factorial. However, social determinants, including those regarding socioeconomic status, social inequalities, health behaviors, and stress, may have implications on these disparities. Exposure to one or more of these social determinants is associated with heightened inflammatory responses, particularly increases in the cytokine interleukin-6 (IL-6), as well as immune system dysfunction. Thus, an amplified effect during COVID-19 could occur, potentially resulting in vulnerable patients experiencing an intensified cytokine storm due to a hyperactive and dysfunctional immune response. Further understanding how social determinants play a mechanistic role in COVID-19 disparities could potentially help reduce health disparities overall and in future pandemics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.