Evidence map›Paper›PMID 33134160›Full record

ArticleFrontiers in oncology2020

M6A RNA Methylation Regulator HNRNPC Contributes to Tumorigenesis and Predicts Prognosis in Glioblastoma Multiforme.

Li-Chong Wang, Shu-Hui Chen, Xiao-Li Shen, Dang-Chi Li, Hai-Yun Liu, Yu-Long Ji, Min Li, Kai Yu, Huan Yang, Jun-Jun Chen and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
8.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 124 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. RNA modification systems as therapeutic targets.Nature reviews. Drug discovery · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. m6A: a novel strategy for osteoporosis treatment.Frontiers in cell and developmental biology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Li-Chong WangDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Shu-Hui ChenDepartment of Radiation Oncology, Jiangxi Cancer Hospital, Nanchang, China.
Xiao-Li ShenDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Dang-Chi LiJiangxi University of Technology High School, Nanchang, China.
Hai-Yun LiuJiangxi University of Traditional Chinese Medicine, Nanchang, China.
Yu-Long JiJiangxi University of Traditional Chinese Medicine, Nanchang, China.
Min LiJiangxi Key Laboratory of Translational Cancer Research, Jiangxi Cancer Hospital, Nanchang, China.
Kai YuDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Huan YangDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Jun-Jun ChenJiangxi Key Laboratory of Translational Cancer Research, Jiangxi Cancer Hospital, Nanchang, China.
Chong-Zhen QinDepartment of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Ming-Ming LuoJiangxi Key Laboratory of Translational Cancer Research, Jiangxi Cancer Hospital, Nanchang, China.
Qian-Xia LinJiangxi University of Traditional Chinese Medicine, Nanchang, China.
Qiao-Li LvJiangxi Key Laboratory of Translational Cancer Research, Department of Head and Neck Surgery, Jiangxi Cancer Hospital, Nanchang, China.
Jiangxi Provincial Cancer Hospital · CNJiangxi University of Traditional Chinese Medicine · CNNanchang University · CNSecond Affiliated Hospital of Nanchang University · CNFirst Affiliated Hospital of Zhengzhou University · CNJiangxi University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma multiforme (GBM) is the most malignant glioma with a high death rate. N6-methyladenosine (m6A) RNA methylation plays an increasingly important role in tumors. The current study aimed to determine the function of the regulators of m6A RNA methylation in GBM. We evaluated the difference, interaction, and correlation of these regulators with TCGA database.

Indexed as

glioblastoma multiformehnRNPCm6Aprognosistumorigenesis

Identifiers

PMID33134160
PMCPMC7578363
OpenAlexW3092209712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.