Evidence map›Paper›PMID 33134136›Full record

ArticleJournal of traditional and complementary medicine2020

Antibacterial oral sprays from kaffir lime (

Somporn Srifuengfung, Nuntavan Bunyapraphatsara, Veena Satitpatipan, Chanwit Tribuddharat, Varaporn Buraphacheep Junyaprasert, Walla Tungrugsasut, Vimol Srisukh

Abstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Antibacterial efficacy ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  7. Review
  8. Article
  9. An assessment of the growth inhibition profiles ofJournal of traditional and complementary medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Somporn SrifuengfungFaculty of Medicine, Siam University, Phet Kasem Road, Phasi Charoen District, Bangkok, 10160, Thailand.
Nuntavan BunyapraphatsaraDepartment of Pharmacognosy, Faculty of Pharmacy, Mahidol University, 447, Sri-Ayutthaya Road, Bangkok, 10400, Thailand.
Veena SatitpatipanDepartment of Pharmacognosy, Faculty of Pharmacy, Mahidol University, 447, Sri-Ayutthaya Road, Bangkok, 10400, Thailand.
Chanwit TribuddharatDepartment of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wang Lang Road, Bangkok 10700, Thailand.
Varaporn Buraphacheep JunyaprasertDepartment of Pharmacy, Faculty of Pharmacy, Mahidol University, 447, Sri-Ayutthaya Road, Bangkok, 10400, Thailand.
Walla TungrugsasutDepartment of Food Chemistry, Faculty of Pharmacy, Mahidol University, 447, Sri-Ayutthaya Road, Bangkok, 10400, Thailand.
Vimol SrisukhDepartment of Food Chemistry, Faculty of Pharmacy, Mahidol University, 447, Sri-Ayutthaya Road, Bangkok, 10400, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimKaffir lime fruit peel oil and Kaffir lime leaf oil have been reported for their activities against respiratory tract pathogens. The purpose of the study was to develop clear oral sprays to be used as a first-defense oral spray. EXPERIMENTAL PROCEDURE: Clear antibacterial oral sprays were prepared and analyzed for their respective active major compounds, using GC-MS. The sprays were tested against a Gr. A streptococcal clinical isolate and 3 standard respiratory tract pathogens, using Broth microdilution method. A 4-month stability test was carried out as well. RESULTS AND

conclusionSix clear oral sprays, three formulae composed of Kaffir lime fruit peel oil (6, 10, 13%v/v KLO) and the other three formulae containing Kaffir lime leaf oil (4, 8, 12%v/v KLLO), were developed. The active compounds in KLO were α-terpineol and terpinene-4-ol whereas that in KLLO was citronellal. All oral sprays exhibited antibacterial activity against one Group A streptococcal clinical isolate and three respiratory pathogenic pathogens,

Indexed as

Alpha-terpineol˚C, Degree CelsiusCitronellalEssential oilg, gramKLLO, Kaffir lime leaf oilKLO, Kaffir lime oilMBC, Minimal bactericidal concentrationmg, milligramMIC, Minimal inhibitory concentrationmin, minuteml, millilitermm, millimeterPharyngitisppm, part per millionSore throatTerpinene-4-ol%v/v, percent in volume by volumeμl, microliterμm, micrometer

Identifiers

PMID33134136
PMCPMC7588327

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.