Evidence map›Paper›PMID 33134126›Full record

ArticlePublic health action2020

Choice architecture-based prescribing tool for TB preventive therapy: a pilot study in South Africa.

G Caturegli, J Materi, A Lombardo, M Milovanovic, N Yende, E Variava, J E Golub, N A Martinson, C J Hoffmann

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Article in Public health action, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

G CaturegliDivision of Infectious Disease, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
J MateriDivision of Infectious Disease, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
A LombardoDivision of Infectious Disease, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
M MilovanovicPerinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg South Africa.
N YendePerinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg South Africa.
E VariavaDepartment of Medicine, Tshepong Hospital, Klerksdorp, South Africa.
J E GolubDivision of Infectious Disease, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
N A MartinsonPerinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg South Africa.
C J HoffmannDivision of Infectious Disease, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

Funding

Prevent TB: Application of choice architecture to implement TB preventive therapy in South AfricaR01AI150432 · NIAID · JOHNS HOPKINS UNIVERSITY · PI HOFFMANN, CHRISTOPHER J · 2020 to 2025
$2.8M
NIAID NIH HHS R01 AI150432
6 · The paper itself

Abstract

backgroundAll people with HIV who screen negative for active tuberculosis (TB) should receive isoniazid preventive therapy (IPT). IPT implementation remains substantially below the 90% WHO target. This study sought to further understanding of IPT prescription by piloting a simplified prescribing approach.

settingPrimary care clinics in Matlosana, South Africa.

designThis was a mixed-methods implementation study.

methodsNine providers were recruited and underwent training on 2018 WHO guidelines. A simplified prescribing tool containing antiretroviral therapy (ART) and IPT prescriptions was introduced into the workflow for 2 weeks. Prescription data were collected from file review. Interviews were conducted with prescribers.

resultsDuring the study period, 41 patients were evaluated for ART initiation; 34 (83%) files used the simplified prescribing tool. Thirty-seven (90%) patients were eligible for same-day ART and IPT initiation, of whom 36 (97%) received IPT prescription. Qualitative interviews identified the following barriers to IPT prescription: cognitive burden, extensive documentation, limited management support, paucity of training, stock-outs, and patient-related factors. Provider acceptability of the tool was favorable, with unanimous recommendation to colleagues on the basis of streamlining documentation and reminding to prescribe.

conclusionsThis simplified prescribing device for IPT was feasible to implement. Streamlining documentation and reminding providers to prescribe can reduce work-flow barriers to IPT provision.

Indexed as

behavioral economicsbehavioral modelingchoice architectureHIVIPTsimplified prescribing

Identifiers

PMID33134126
PMCPMC7577007

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.