Evidence map›Paper›PMID 33134125›Full record

ArticlePublic health action2020

How much do Indians pay for tuberculosis treatment? A cost analysis.

P Sinha, M Carwile, A Bhargava, C Cintron, C Acuna-Villaorduna, S Lakshminarayan, A F Liu, N Kulatilaka, L Locks, N S Hochberg

Open access · diamondAbstract read
In one paragraph

Article in Public health action, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Clearing the air: microcosting the carbon impact of drug-susceptible pulmonary TB treatment.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2024
    Article
  11. Review
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  18. Determination of Direct and Indirect Costs Incurred by Tuberculosis Patients During Diagnosis and Treatment in Urban Areas of South Gujarat: A Mixed Method Approach.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

P SinhaSection of Infectious Diseases, Department of Medicine, Boston University School of Medicine, MA, USA.
M CarwileDepartment of Global Health, Boston University School of Public Health, MA, USA.
A BhargavaDepartment of Medicine, Yenepoya Medical College, Mangalore, India.
C CintronSection of Infectious Diseases, Department of Medicine, Boston University School of Medicine, MA, USA.
C Acuna-VillaordunaSection of Infectious Diseases, Department of Medicine, Boston University School of Medicine, MA, USA.
S LakshminarayanDepartment of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India.
A F LiuDepartment of Gastroenterology, Brigham and Women's Hospital, Boston, MA, USA.
N KulatilakaSusilo Institute for Ethics in a Global Economy, Boston University Questrom School of Business, Boston, MA, USA.
L LocksDepartment of Health Sciences, Sargent College, Boston University College of Health & Rehabilitation Sciences, Boston, MA, USA.
N S HochbergSection of Infectious Diseases, Department of Medicine, Boston University School of Medicine, MA, USA.
Boston University · USBrigham and Women's Hospital · USJawaharlal Institute of Post Graduate Medical Education and Research · INMcGill University · CA

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
BU Clinical HIV/AIDS Research Training Program (BU-CHART)T32AI052074 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Benjamin P. Linas · 2003 to 2026
$6.7M
NCATS NIH HHS UL1 TR001430NIAID NIH HHS T32 AI052074
6 · The paper itself

Abstract

settingIndia's National Tuberculosis Elimination Programme (NTEP) covers diagnostic and therapeutic costs of TB treatment. However, persons living with TB (PLWTB) continue to experience financial distress due to direct costs (payment for testing, treatment, travel, hospitalization, and nutritional supplements) and indirect costs (lost wages, loan interest, and cost of domestic helpers).

objectiveTo analyze the magnitude and pattern of TB-related costs from the perspective of Indian PLWTB.

designWe identified relevant articles using key search terms ('tuberculosis,' 'India,' 'cost,' 'expenditures,' 'financing,' 'catastrophic' and 'out of pocket') and calculated variance-weighted mean costs.

resultsIndian patients incur substantial direct costs (mean: US$46.8). Mean indirect costs (US$666.6) constitute 93.4% of the net costs. Mean direct costs before diagnosis can be up to four-fold that of costs during treatment. Treatment in the private sector can result in costs up to six-fold higher than in government facilities. As many as one in three PLWTB in India experience catastrophic costs.

conclusionPLWTB in India face high direct and indirect costs. Priority interventions to realize India's goal of eliminating catastrophic costs from TB include decreasing diagnostic delays through active case finding, reducing the need for travel, improving awareness and perception of NTEP services, and ensuring sufficient reimbursement for inpatient TB care.

Indexed as

catastrophic costcopingdistress financingindirect costsout-of-pocket

Identifiers

PMID33134125
PMCPMC7577002
OpenAlexW3093847127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.