Evidence map›Paper›PMID 33133776›Full record

ArticleCurrent ophthalmology reports2019

Molecular Biomarkers for Glaucoma.

Gala Beykin, Jeffrey L Goldberg

Open access · greenAbstract read
In one paragraph

Article in Current ophthalmology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Tear fluid database: a reference website for tear fluid proteomics.Database : the journal of biological databases and curation · 2026
    Article
  3. Review
  4. Article
  5. Clinical Tear Fluid Proteomics-A Novel Tool in Glaucoma Research.International journal of molecular sciences · 2022
    Review
  6. Protein Biomarkers in Glaucoma: A Review.Journal of clinical medicine · 2021
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gala BeykinByers Eye Institute at Stanford University, 2452 Watson Ct, Palo Alto, CA 94303.
Jeffrey L GoldbergByers Eye Institute at Stanford University, 2452 Watson Ct, Palo Alto, CA 94303.
Smith-Kettlewell Eye Research Institute · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
Structural and functional tests of ganglion cell damage in glaucomaR01EY030361 · NEI · STANFORD UNIVERSITY · PI GOLDBERG, JEFFREY L, NORCIA, ANTHONY M · 2019 to 2022
$2.1M
Development, Validation and Application of Metabolic Imaging in GlaucomaR01EY028287 · NEI · STANFORD UNIVERSITY · PI DUBRA, ALFREDO, GOLDBERG, JEFFREY L · 2017 to 2019
$1.1M
NEI NIH HHS P30 EY026877NEI NIH HHS R01 EY028287NEI NIH HHS R01 EY030361
6 · The paper itself

Abstract

purpose of reviewThis article summarizes the current studies on molecular biomarkers with potential implications in diagnosis, prognosis, and response to treatment in patients with glaucoma. RECENT

findingsImportant advances have occurred in the understanding of the pathogenesis of glaucomatous neurodegeneration. Protein biomarkers associated with inflammatory, neurodegenerative, and other molecular pathways have been described in glaucoma patients in tear film, aqueous fluid, vitreous fluid, and serum, however, we are still far from having a clear picture of the whole molecular network that relates to the disease and its implications in clinical use. SUMMARY: Although more studies are needed, current and emerging molecular biomarkers candidates in glaucoma may eventually transition into clinical use and contribute to outline the concept of precision medicine and precision health in glaucoma.

Indexed as

biomarkersGlaucomaoptic nerve degeneration

Identifiers

PMID33133776
PMCPMC7597904
OpenAlexW2963218687

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.