Evidence map›Paper›PMID 33133361›Full record

ArticleMethodist DeBakey cardiovascular journal

BRASH Syndrome with Hyperkalemia: An Under-Recognized Clinical Condition.

Abdul Wahab Arif, Muhammad Shahzeb Khan, Abdallah Masri, Benjamin Mba, Muhammad Talha Ayub, Rami Doukky

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Methodist DeBakey cardiovascular journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Abdul Wahab ArifCOOK COUNTY HOSPITAL, CHICAGO, ILLINOIS.
Muhammad Shahzeb KhanCOOK COUNTY HOSPITAL, CHICAGO, ILLINOIS.
Abdallah MasriCOOK COUNTY HOSPITAL, CHICAGO, ILLINOIS.
Benjamin MbaCOOK COUNTY HOSPITAL, CHICAGO, ILLINOIS.
Muhammad Talha AyubRUSH UNIVERSITY MEDICAL CENTER, CHICAGO, ILLINOIS.
Rami DoukkyCOOK COUNTY HOSPITAL, CHICAGO, ILLINOIS.
John H. Stroger, Jr. Hospital of Cook County · USRush University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BRASH syndrome is characterized by bradycardia, renal failure, use of an atrioventricular nodal blocker (AVNB), shock, and hyperkalemia. These symptoms represent an ongoing vicious cycle in a patient with a low glomerular filtration rate taking an AVNB. Decreased clearance of the medication and hyperkalemia associated with renal failure synergize to cause bradycardia and hypoperfusion. This reaction causes renal function to worsen, thereby perpetuating the cycle of BRASH syndrome.

Indexed as

Antihypertensive AgentsAtrioventricular NodeBradycardiaDiltiazemFemaleGlomerular Filtration RateHumansHyperkalemiaKidneyMiddle AgedRenal Insufficiency, ChronicSyndromeTreatment OutcomeAntihypertensive AgentsDiltiazematrioventricular nodal blockerbradycardiaBRASH syndromehyperkalemiarenal failureshock

Identifiers

PMID33133361
PMCPMC7587309
OpenAlexW3097142006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.