Evidence map›Paper›PMID 33133139›Full record

ArticleFrontiers in genetics2020

A Machine Learning Approach to Predicting Autism Risk Genes: Validation of Known Genes and Discovery of New Candidates.

Ying Lin, Shiva Afshar, Anjali M Rajadhyaksha, James B Potash, Shizhong Han

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 59 citations in OpenAlex.

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  6. First Report of a FamiliarBalkan journal of medical genetics : BJMG · 2025
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  20. Regulation of MAPK Signaling Pathways by the Large HERC Ubiquitin Ligases.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ying LinDepartment of Industrial Engineering, University of Houston, Houston, TX, United States.
Shiva AfsharDepartment of Industrial Engineering, University of Houston, Houston, TX, United States.
Anjali M RajadhyakshaDivision of Pediatric Neurology, Department of Pediatrics, Weill Cornell Medicine, New York, NY, United States.
James B PotashDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Shizhong HanDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Johns Hopkins University · USUniversity of Houston · USMIND Research Institute · US

Funding

A SYSTEMS APPROACH TO THE GENETIC STUDY OF ALCOHOL DEPENDENCER01AA024486 · NIAAA · UNIVERSITY OF IOWA · PI HAN, SHIZHONG, TAN, KAI · 2017 to 2020
$1.6M
Fine mapping a gene sub-network underlying alcohol dependenceR01AA022994 · NIAAA · UNIVERSITY OF IOWA · PI HAN, SHIZHONG · 2014 to 2017
$1.3M
NIAAA NIH HHS R01 AA022994NIAAA NIH HHS R01 AA024486
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with a strong genetic basis. The role of

Indexed as

autismconstraintde novo mutationgene expressionmachine learning

Identifiers

PMID33133139
PMCPMC7513695
OpenAlexW3085184829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.