Evidence map›Paper›PMID 33132925›Full record

ArticleFrontiers in psychiatry2020

Dissociating Slow Responses From Slow Responding.

Gayatri Salunkhe, Bernd Feige, Christopher W N Saville, Maria Elena Stefanou, David Linden, Stephan Bender, Andrea Berger, Nikolaos Smyrnis, Monica Biscaldi, Christoph Klein

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In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gayatri SalunkheDepartment of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Bernd FeigeDepartment of Psychiatry and Psychotherapy, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Christopher W N SavilleSchool of Psychology, Bangor University, Bangor, United Kingdom.
Maria Elena StefanouDepartment of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
David LindenSchool for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.
Stephan BenderDepartment of Child and Adolescent Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany.
Andrea BergerDepartment of Psychology, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Nikolaos SmyrnisDepartment of Psychiatry, National and Kapodistrian University of Athens, Medical School, Eginition Hospital, Athens, Greece.
Monica BiscaldiDepartment of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Christoph KleinDepartment of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased Intra-Subject Variability (ISV) is a candidate endophenotype of ADHD. ISV's relationship with response speed is highly relevant for ADHD as patients are highly variable but typically no slower than controls. This brief report addresses the relationship between variability and speed by employing dimensional analyses for differentiated performance measures, with a particular focus on the ex-Gaussian measures, across relevant ADHD studies and in young healthy adults (N = 70). For both patients with ADHD and healthy adults, we found that reaction time standard deviation and mean reaction time were strongly correlated, thus failing to dissociate, but ex-Gaussian tau (τ) shared only little variance with Gaussian mu (μ), thus dissociating slow responses (τ) from response speed or-if given-slow responding (μ). Our results highlight the utility of employing the ex-Gaussian measures to disentangle ISV and speed, particularly for ADHD data as patients make more slow responses but are not overall slower than typical controls.

Indexed as

attention-deficit/hyperactivity disorder (ADHD)ex-Gaussian modelingintra-subject variabilityprincipal components analysesresponse speed

Identifiers

PMID33132925
PMCPMC7562713

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.