Evidence map›Paper›PMID 33132878›Full record

ArticleFrontiers in human neuroscience2020

Neural Correlates of Smartphone Dependence in Adolescents.

Olga Tymofiyeva, Justin P Yuan, Roma Kidambi, Chiung-Yu Huang, Eva Henje, Mark L Rubinstein, Namasvi Jariwala, Jeffrey E Max, Tony T Yang, Duan Xu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Motivation Profiles Towards Academic Reading, Substance-Related and Problematic Behaviors in Future Teachers.European journal of investigation in health, psychology and education · 2026
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  18. Reduced Volume of a Brainstem Substructure in Adolescents with Problematic Smartphone Use.Soa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry · 2021
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Olga TymofiyevaDepartment of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States.
Justin P YuanDepartment of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States.
Roma KidambiDepartment of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States.
Chiung-Yu HuangDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States.
Eva HenjeDepartment of Psychiatry and Behavioral Sciences, The Langley Porter Psychiatric Institute, Division of Child and Adolescent Psychiatry, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, United States.
Mark L RubinsteinDepartment of Pediatrics, University of California, San Francisco, San Francisco, CA, United States.
Namasvi JariwalaDepartment of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States.
Jeffrey E MaxDepartment of Psychiatry, University of California, San Diego, Rady Children's Hospital-San Diego, San Diego, CA, United States.
Tony T YangDepartment of Psychiatry and Behavioral Sciences, The Langley Porter Psychiatric Institute, Division of Child and Adolescent Psychiatry, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, United States.
Duan XuDepartment of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States.
University of California, San Francisco · USLangley Porter Psychiatric Hospital and Clinics · USStanford University · USUniversity of California, San Diego · US

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
Magnetoencephalography and Neurobehavioral Outcome of Pediatric Traumatic Brain InjuryR01HD088438 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MAX, JEFFREY EDWIN · 2017 to 2021
$3.1M
Towards Baby Brain Connectome: a Study of Newborn Brain NetworksR01HD072074 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HESS, CHRISTOPHER PAUL, XU, DUAN · 2013 to 2017
$3.0M
A Cross-Sectional and Longitudinal Functional MRI Study of Adolescent DepressionR01MH085734 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YANG, TONY TUNG-I · 2010 to 2014
$2.7M
Neural mechanisms of meditation training in healthy and depressed adolescents: An MRI connectome studyR61AT009864 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TYMOFIYEVA, OLGA, YANG, TONY TUNG-I · 2019 to 2020
$822k
A Network Approach to Study Brain Plasticity in Children with Cognitive TrainingR21AT009173 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TYMOFIYEVA, OLGA · 2016 to 2017
$436k
NCATS NIH HHS UL1 TR001872NCCIH NIH HHS R21 AT009173NCCIH NIH HHS R61 AT009864NICHD NIH HHS R01 HD072074NICHD NIH HHS R01 HD088438NIMH NIH HHS R01 MH085734
6 · The paper itself

Abstract

Increases in depressive and suicide-related symptoms among United States adolescents have been recently linked to increased use of smartphones. Understanding of the brain mechanisms that underlie the potential smartphone dependence may help develop interventions to address this important problem. In this exploratory study, we investigated the neural mechanisms underlying potential smartphone dependence in a sample of 19 adolescent volunteers who completed self-assessments of their smartphone dependence, depressive symptoms, and sleep problems. All 19 adolescents underwent diffusion MRI that allowed for assessment of white matter structural connectivity within the framework of connectomics. Based on previous literature on the neurobiology of addiction, we hypothesized a disruption of network centrality of three nodes in the mesolimbic network: Nucleus Accumbens, anterior cingulate cortex, and amygdala. Our results showed positive correlations between the node centrality of the right amygdala and self-reported smartphone dependence, between smartphone dependence and sleep problems, and between sleep problems and depressive symptoms. A higher phone dependence was observed in females compared to males. Supported by these results, we propose a model of how smartphone dependence can be linked to aberrations in brain networks, sex, sleep disturbances, and depression in adolescents.

Indexed as

adolescentbrain connectivitydepressionsleepsmartphone dependence

Identifiers

PMID33132878
PMCPMC7577047
OpenAlexW3092150346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.